Haug JL - Search Results

1

Impact of gene expression profiling-based risk stratification in patients with myeloma receiving initial therapy with lenalidomide and dexamethasone.

Kumar SK, Uno H, Jacobus SJ, Van Wier SA, Ahmann GJ, Henderson KJ, Callander NS, Haug JL, Siegel DS, Greipp PR, Fonseca R, Rajkumar SV. Kumar SK, et al. Among authors: haug jl. Blood. 2011 Oct 20;118(16):4359-62. doi: 10.1182/blood-2011-03-342089. Epub 2011 Aug 22. Blood. 2011. PMID: 21860025 Free PMC article. Clinical Trial.

2

Bone marrow angiogenic ability and expression of angiogenic cytokines in myeloma: evidence favoring loss of marrow angiogenesis inhibitory activity with disease progression.

Kumar S, Witzig TE, Timm M, Haug J, Wellik L, Kimlinger TK, Greipp PR, Rajkumar SV. Kumar S, et al. Blood. 2004 Aug 15;104(4):1159-65. doi: 10.1182/blood-2003-11-3811. Epub 2004 May 6. Blood. 2004. PMID: 15130943 Free article.

3

R-(-)-gossypol (AT-101) activates programmed cell death in multiple myeloma cells.

Kline MP, Rajkumar SV, Timm MM, Kimlinger TK, Haug JL, Lust JA, Greipp PR, Kumar S. Kline MP, et al. Among authors: haug jl. Exp Hematol. 2008 May;36(5):568-76. doi: 10.1016/j.exphem.2008.01.003. Epub 2008 Mar 17. Exp Hematol. 2008. PMID: 18346839 Free PMC article.

4

Thymoglobulin targets multiple plasma cell antigens and has in vitro and in vivo activity in multiple myeloma.

Timm MM, Kimlinger TK, Haug JL, Kline MP, Greipp PR, Rajkumar SV, Kumar SK. Timm MM, et al. Among authors: haug jl. Leukemia. 2006 Oct;20(10):1863-9. doi: 10.1038/sj.leu.2404359. Epub 2006 Aug 17. Leukemia. 2006. PMID: 16932343

5

ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells.

Kline MP, Rajkumar SV, Timm MM, Kimlinger TK, Haug JL, Lust JA, Greipp PR, Kumar S. Kline MP, et al. Among authors: haug jl. Leukemia. 2007 Jul;21(7):1549-60. doi: 10.1038/sj.leu.2404719. Epub 2007 Apr 26. Leukemia. 2007. PMID: 17460700

6

Plasma levels of tumour necrosis factor alpha and interleukin-6 predict progression-free survival following thalidomide therapy in patients with previously untreated multiple myeloma.

Thompson MA, Witzig TE, Kumar S, Timm MM, Haug J, Fonseca R, Greipp PR, Lust JA, Rajkumar SV. Thompson MA, et al. Br J Haematol. 2003 Oct;123(2):305-8. doi: 10.1046/j.1365-2141.2003.04605.x. Br J Haematol. 2003. PMID: 14531913 Free article. Clinical Trial.

7

Multiple mechanisms contribute to the synergistic anti-myeloma activity of the pan-histone deacetylase inhibitor LBH589 and the rapalog RAD001.

Ramakrishnan V, Kimlinger T, Timm M, Haug J, Rajkumar SV, Kumar S. Ramakrishnan V, et al. Leuk Res. 2014 Nov;38(11):1358-66. doi: 10.1016/j.leukres.2014.09.004. Epub 2014 Sep 28. Leuk Res. 2014. PMID: 25282334 Free PMC article.

8

Expression of VEGF and its receptors by myeloma cells.

Kumar S, Witzig TE, Timm M, Haug J, Wellik L, Fonseca R, Greipp PR, Rajkumar SV. Kumar S, et al. Leukemia. 2003 Oct;17(10):2025-31. doi: 10.1038/sj.leu.2403084. Leukemia. 2003. PMID: 14513053

9

Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs.

Ramakrishnan V, Timm M, Haug JL, Kimlinger TK, Wellik LE, Witzig TE, Rajkumar SV, Adjei AA, Kumar S. Ramakrishnan V, et al. Among authors: haug jl. Oncogene. 2010 Feb 25;29(8):1190-202. doi: 10.1038/onc.2009.403. Epub 2009 Nov 23. Oncogene. 2010. PMID: 19935717 Free PMC article.

10

Anti-myeloma activity of Akt inhibition is linked to the activation status of PI3K/Akt and MEK/ERK pathway.

Ramakrishnan V, Kimlinger T, Haug J, Painuly U, Wellik L, Halling T, Rajkumar SV, Kumar S. Ramakrishnan V, et al. PLoS One. 2012;7(11):e50005. doi: 10.1371/journal.pone.0050005. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185517 Free PMC article.

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