Vassilev LT - Search Results

1

Stabilisation of p53 enhances reovirus-induced apoptosis and virus spread through p53-dependent NF-κB activation.

Pan D, Pan LZ, Hill R, Marcato P, Shmulevitz M, Vassilev LT, Lee PW. Pan D, et al. Among authors: vassilev lt. Br J Cancer. 2011 Sep 27;105(7):1012-22. doi: 10.1038/bjc.2011.325. Epub 2011 Aug 23. Br J Cancer. 2011. PMID: 21863032 Free PMC article.

2

Targeting the p53-MDM2 interaction to treat cancer.

Klein C, Vassilev LT. Klein C, et al. Among authors: vassilev lt. Br J Cancer. 2004 Oct 18;91(8):1415-9. doi: 10.1038/sj.bjc.6602164. Br J Cancer. 2004. PMID: 15452548 Free PMC article. Review.

3

Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma.

Ohnstad HO, Castro R, Sun J, Heintz KM, Vassilev LT, Bjerkehagen B, Kresse SH, Meza-Zepeda LA, Myklebost O. Ohnstad HO, et al. Among authors: vassilev lt. Cancer. 2013 Mar 1;119(5):1013-22. doi: 10.1002/cncr.27837. Epub 2012 Nov 16. Cancer. 2013. PMID: 23165797 Free article.

4

Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors.

Carvajal D, Tovar C, Yang H, Vu BT, Heimbrook DC, Vassilev LT. Carvajal D, et al. Among authors: vassilev lt. Cancer Res. 2005 Mar 1;65(5):1918-24. doi: 10.1158/0008-5472.CAN-04-3576. Cancer Res. 2005. PMID: 15753391

5

Depletion of mutant p53 and cytotoxicity of histone deacetylase inhibitors.

Blagosklonny MV, Trostel S, Kayastha G, Demidenko ZN, Vassilev LT, Romanova LY, Bates S, Fojo T. Blagosklonny MV, et al. Among authors: vassilev lt. Cancer Res. 2005 Aug 15;65(16):7386-92. doi: 10.1158/0008-5472.CAN-04-3433. Cancer Res. 2005. PMID: 16103091

6

Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1.

Ambrosini G, Sambol EB, Carvajal D, Vassilev LT, Singer S, Schwartz GK. Ambrosini G, et al. Among authors: vassilev lt. Oncogene. 2007 May 24;26(24):3473-81. doi: 10.1038/sj.onc.1210136. Epub 2006 Dec 4. Oncogene. 2007. PMID: 17146434

7

Enhanced tumor cell kill by combined treatment with a small-molecule antagonist of mouse double minute 2 and adenoviruses encoding p53.

Graat HC, Carette JE, Schagen FH, Vassilev LT, Gerritsen WR, Kaspers GJ, Wuisman PI, van Beusechem VW. Graat HC, et al. Among authors: vassilev lt. Mol Cancer Ther. 2007 May;6(5):1552-61. doi: 10.1158/1535-7163.MCT-06-0631. Mol Cancer Ther. 2007. PMID: 17513604

8

Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin.

Efeyan A, Ortega-Molina A, Velasco-Miguel S, Herranz D, Vassilev LT, Serrano M. Efeyan A, et al. Among authors: vassilev lt. Cancer Res. 2007 Aug 1;67(15):7350-7. doi: 10.1158/0008-5472.CAN-07-0200. Cancer Res. 2007. PMID: 17671205

9

Pharmacologic p53 activation blocks cell cycle progression but fails to induce senescence in epithelial cancer cells.

Huang B, Deo D, Xia M, Vassilev LT. Huang B, et al. Among authors: vassilev lt. Mol Cancer Res. 2009 Sep;7(9):1497-509. doi: 10.1158/1541-7786.MCR-09-0144. Epub 2009 Sep 8. Mol Cancer Res. 2009. PMID: 19737973 Free article.

10

Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML.

Carter BZ, Mak DH, Schober WD, Koller E, Pinilla C, Vassilev LT, Reed JC, Andreeff M. Carter BZ, et al. Among authors: vassilev lt. Blood. 2010 Jan 14;115(2):306-14. doi: 10.1182/blood-2009-03-212563. Epub 2009 Nov 6. Blood. 2010. PMID: 19897582 Free PMC article.

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