Youle RJ - Search Results

1

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells.

Kim KY, Stevens MV, Akter MH, Rusk SE, Huang RJ, Cohen A, Noguchi A, Springer D, Bocharov AV, Eggerman TL, Suen DF, Youle RJ, Amar M, Remaley AT, Sack MN. Kim KY, et al. Among authors: youle rj. J Clin Invest. 2011 Sep;121(9):3701-12. doi: 10.1172/JCI44736. Epub 2011 Aug 25. J Clin Invest. 2011. PMID: 21865652 Free PMC article.

2

Mitochondrial dynamics and apoptosis.

Suen DF, Norris KL, Youle RJ. Suen DF, et al. Among authors: youle rj. Genes Dev. 2008 Jun 15;22(12):1577-90. doi: 10.1101/gad.1658508. Genes Dev. 2008. PMID: 18559474 Free PMC article. Review.

3

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.

Narendra D, Tanaka A, Suen DF, Youle RJ. Narendra D, et al. Among authors: youle rj. J Cell Biol. 2008 Dec 1;183(5):795-803. doi: 10.1083/jcb.200809125. Epub 2008 Nov 24. J Cell Biol. 2008. PMID: 19029340 Free PMC article.

4

Parkin-induced mitophagy in the pathogenesis of Parkinson disease.

Narendra D, Tanaka A, Suen DF, Youle RJ. Narendra D, et al. Among authors: youle rj. Autophagy. 2009 Jul;5(5):706-8. doi: 10.4161/auto.5.5.8505. Epub 2009 Jul 22. Autophagy. 2009. PMID: 19377297

5

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.

Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, Cookson MR, Youle RJ. Narendra DP, et al. Among authors: youle rj. PLoS Biol. 2010 Jan 26;8(1):e1000298. doi: 10.1371/journal.pbio.1000298. PLoS Biol. 2010. PMID: 20126261 Free PMC article.

6

Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells.

Suen DF, Narendra DP, Tanaka A, Manfredi G, Youle RJ. Suen DF, et al. Among authors: youle rj. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11835-40. doi: 10.1073/pnas.0914569107. Epub 2010 Jun 14. Proc Natl Acad Sci U S A. 2010. PMID: 20547844 Free PMC article.

7

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.

Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ. Tanaka A, et al. Among authors: youle rj. J Cell Biol. 2010 Dec 27;191(7):1367-80. doi: 10.1083/jcb.201007013. Epub 2010 Dec 20. J Cell Biol. 2010. PMID: 21173115 Free PMC article.

8

Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control.

Narendra DP, Youle RJ. Narendra DP, et al. Among authors: youle rj. Antioxid Redox Signal. 2011 May 15;14(10):1929-38. doi: 10.1089/ars.2010.3799. Epub 2011 Mar 3. Antioxid Redox Signal. 2011. PMID: 21194381 Free PMC article. Review.

9

Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy.

Joo JH, Dorsey FC, Joshi A, Hennessy-Walters KM, Rose KL, McCastlain K, Zhang J, Iyengar R, Jung CH, Suen DF, Steeves MA, Yang CY, Prater SM, Kim DH, Thompson CB, Youle RJ, Ney PA, Cleveland JL, Kundu M. Joo JH, et al. Among authors: youle rj. Mol Cell. 2011 Aug 19;43(4):572-85. doi: 10.1016/j.molcel.2011.06.018. Mol Cell. 2011. PMID: 21855797 Free PMC article.

10

PINK1- and Parkin-mediated mitophagy at a glance.

Jin SM, Youle RJ. Jin SM, et al. Among authors: youle rj. J Cell Sci. 2012 Feb 15;125(Pt 4):795-9. doi: 10.1242/jcs.093849. J Cell Sci. 2012. PMID: 22448035 Free PMC article. No abstract available.

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