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Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro.
Takata F, Dohgu S, Matsumoto J, Takahashi H, Machida T, Wakigawa T, Harada E, Miyaji H, Koga M, Nishioku T, Yamauchi A, Kataoka Y. Takata F, et al. Among authors: machida t. J Neuroinflammation. 2011 Aug 26;8:106. doi: 10.1186/1742-2094-8-106. J Neuroinflammation. 2011. PMID: 21867555 Free PMC article.
Metformin induces up-regulation of blood-brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells.
Takata F, Dohgu S, Matsumoto J, Machida T, Kaneshima S, Matsuo M, Sakaguchi S, Takeshige Y, Yamauchi A, Kataoka Y. Takata F, et al. Among authors: machida t. Biochem Biophys Res Commun. 2013 Apr 19;433(4):586-90. doi: 10.1016/j.bbrc.2013.03.036. Epub 2013 Mar 21. Biochem Biophys Res Commun. 2013. PMID: 23523792
859 results