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A randomized trial of the efficacy and safety of quilizumab in adults with inadequately controlled allergic asthma.
Harris JM, Maciuca R, Bradley MS, Cabanski CR, Scheerens H, Lim J, Cai F, Kishnani M, Liao XC, Samineni D, Zhu R, Cochran C, Soong W, Diaz JD, Perin P, Tsukayama M, Dimov D, Agache I, Kelsen SG. Harris JM, et al. Respir Res. 2016 Mar 18;17:29. doi: 10.1186/s12931-016-0347-2. Respir Res. 2016. PMID: 26993628 Free PMC article. Clinical Trial.
Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production.
Gauvreau GM, Harris JM, Boulet LP, Scheerens H, Fitzgerald JM, Putnam WS, Cockcroft DW, Davis BE, Leigh R, Zheng Y, Dahlén B, Wang Y, Maciuca R, Mayers I, Liao XC, Wu LC, Matthews JG, O'Byrne PM. Gauvreau GM, et al. Among authors: harris jm. Sci Transl Med. 2014 Jul 2;6(243):243ra85. doi: 10.1126/scitranslmed.3008961. Sci Transl Med. 2014. PMID: 24990880 Clinical Trial.
Disconnect between sputum neutrophils and other measures of airway inflammation in asthma.
Arron JR, Choy DF, Laviolette M, Kelsen SG, Hatab A, Leigh R, Thomson NC, Bleecker ER, Olivenstein R, Avila PC, Jarjour NN, Castro M, Gauvreau GM, Good JT, Kline JN, Mansur A, Mayers I, Heaney LG, Hamid Q, Harris JM. Arron JR, et al. Among authors: harris jm. Eur Respir J. 2014 Feb;43(2):627-9. doi: 10.1183/09031936.00117013. Epub 2013 Oct 31. Eur Respir J. 2014. PMID: 24176993 Free article. No abstract available.
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients.
Jia G, Erickson RW, Choy DF, Mosesova S, Wu LC, Solberg OD, Shikotra A, Carter R, Audusseau S, Hamid Q, Bradding P, Fahy JV, Woodruff PG, Harris JM, Arron JR; Bronchoscopic Exploratory Research Study of Biomarkers in Corticosteroid-refractory Asthma (BOBCAT) Study Group. Jia G, et al. Among authors: harris jm. J Allergy Clin Immunol. 2012 Sep;130(3):647-654.e10. doi: 10.1016/j.jaci.2012.06.025. Epub 2012 Aug 1. J Allergy Clin Immunol. 2012. PMID: 22857879 Free PMC article.
747 results