Walker GC - Search Results

1

Functional characterization of bacterial sRNAs using a network biology approach.

Modi SR, Camacho DM, Kohanski MA, Walker GC, Collins JJ. Modi SR, et al. Among authors: walker gc. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15522-7. doi: 10.1073/pnas.1104318108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876160 Free PMC article.

2

Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli.

Cohen SE, Lewis CA, Mooney RA, Kohanski MA, Collins JJ, Landick R, Walker GC. Cohen SE, et al. Among authors: walker gc. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15517-22. doi: 10.1073/pnas.1005203107. Epub 2010 Aug 9. Proc Natl Acad Sci U S A. 2010. PMID: 20696893 Free PMC article.

3

Antibiotics induce redox-related physiological alterations as part of their lethality.

Dwyer DJ, Belenky PA, Yang JH, MacDonald IC, Martell JD, Takahashi N, Chan CT, Lobritz MA, Braff D, Schwarz EG, Ye JD, Pati M, Vercruysse M, Ralifo PS, Allison KR, Khalil AS, Ting AY, Walker GC, Collins JJ. Dwyer DJ, et al. Among authors: walker gc. Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2100-9. doi: 10.1073/pnas.1401876111. Epub 2014 May 6. Proc Natl Acad Sci U S A. 2014. PMID: 24803433 Free PMC article.

4

Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.

Davies BW, Kohanski MA, Simmons LA, Winkler JA, Collins JJ, Walker GC. Davies BW, et al. Among authors: walker gc. Mol Cell. 2009 Dec 11;36(5):845-60. doi: 10.1016/j.molcel.2009.11.024. Mol Cell. 2009. PMID: 20005847 Free PMC article.

5

Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria.

Pandey SP, Winkler JA, Li H, Camacho DM, Collins JJ, Walker GC. Pandey SP, et al. Among authors: walker gc. BMC Genomics. 2014 Feb 11;15:121. doi: 10.1186/1471-2164-15-121. BMC Genomics. 2014. PMID: 24511998 Free PMC article.

6

Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality.

Takahashi N, Gruber CC, Yang JH, Liu X, Braff D, Yashaswini CN, Bhubhanil S, Furuta Y, Andreescu S, Collins JJ, Walker GC. Takahashi N, et al. Among authors: walker gc. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9164-9169. doi: 10.1073/pnas.1707466114. Epub 2017 Aug 9. Proc Natl Acad Sci U S A. 2017. PMID: 28794281 Free PMC article.

7

A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action.

Yang JH, Wright SN, Hamblin M, McCloskey D, Alcantar MA, Schrübbers L, Lopatkin AJ, Satish S, Nili A, Palsson BO, Walker GC, Collins JJ. Yang JH, et al. Among authors: walker gc. Cell. 2019 May 30;177(6):1649-1661.e9. doi: 10.1016/j.cell.2019.04.016. Epub 2019 May 9. Cell. 2019. PMID: 31080069 Free PMC article.

8

Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics.

Foti JJ, Devadoss B, Winkler JA, Collins JJ, Walker GC. Foti JJ, et al. Among authors: walker gc. Science. 2012 Apr 20;336(6079):315-9. doi: 10.1126/science.1219192. Science. 2012. PMID: 22517853 Free PMC article.

9

Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage.

Belenky P, Ye JD, Porter CB, Cohen NR, Lobritz MA, Ferrante T, Jain S, Korry BJ, Schwarz EG, Walker GC, Collins JJ. Belenky P, et al. Among authors: walker gc. Cell Rep. 2015 Nov 3;13(5):968-80. doi: 10.1016/j.celrep.2015.09.059. Epub 2015 Oct 22. Cell Rep. 2015. PMID: 26565910 Free PMC article.

10

Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality.

Lobritz MA, Andrews IW, Braff D, Porter CBM, Gutierrez A, Furuta Y, Cortes LBG, Ferrante T, Bening SC, Wong F, Gruber C, Bakerlee CW, Lambert G, Walker GC, Dwyer DJ, Collins JJ. Lobritz MA, et al. Among authors: walker gc. Cell Chem Biol. 2022 Feb 17;29(2):276-286.e4. doi: 10.1016/j.chembiol.2021.12.010. Epub 2022 Jan 5. Cell Chem Biol. 2022. PMID: 34990601 Free PMC article.

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