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New trends in the design of drugs against Alzheimer's disease.
Francotte P, Graindorge E, Boverie S, de Tullio P, Pirotte B. Francotte P, et al. Among authors: pirotte b. Curr Med Chem. 2004 Jul;11(13):1757-78. doi: 10.2174/0929867043364946. Curr Med Chem. 2004. PMID: 15279580 Review.
In search of novel AMPA potentiators.
Francotte P, de Tullio P, Fraikin P, Counerotte S, Goffin E, Pirotte B. Francotte P, et al. Among authors: pirotte b. Recent Pat CNS Drug Discov. 2006 Nov;1(3):239-46. doi: 10.2174/157488906778773661. Recent Pat CNS Drug Discov. 2006. PMID: 18221205 Review.
New fluorinated 1,2,4-benzothiadiazine 1,1-dioxides: discovery of an orally active cognitive enhancer acting through potentiation of the 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors.
Francotte P, Goffin E, Fraikin P, Lestage P, Van Heugen JC, Gillotin F, Danober L, Thomas JY, Chiap P, Caignard DH, Pirotte B, de Tullio P. Francotte P, et al. Among authors: pirotte b. J Med Chem. 2010 Feb 25;53(4):1700-11. doi: 10.1021/jm901495t. J Med Chem. 2010. PMID: 20108934 Free article.
AMPA receptor positive allosteric modulators: a patent review.
Pirotte B, Francotte P, Goffin E, de Tullio P. Pirotte B, et al. Expert Opin Ther Pat. 2013 May;23(5):615-28. doi: 10.1517/13543776.2013.770840. Epub 2013 Feb 13. Expert Opin Ther Pat. 2013. PMID: 23405869 Review.
Development of thiophenic analogues of benzothiadiazine dioxides as new powerful potentiators of 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) receptors.
Francotte P, Goffin E, Fraikin P, Graindorge E, Lestage P, Danober L, Challal S, Rogez N, Nosjean O, Caignard DH, Pirotte B, de Tullio P. Francotte P, et al. Among authors: pirotte b. J Med Chem. 2013 Oct 24;56(20):7838-50. doi: 10.1021/jm400676g. Epub 2013 Oct 3. J Med Chem. 2013. PMID: 24090223
251 results