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Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.
Kumadaki S, Karasawa T, Matsuzaka T, Ema M, Nakagawa Y, Nakakuki M, Saito R, Yahagi N, Iwasaki H, Sone H, Takekoshi K, Yatoh S, Kobayashi K, Takahashi A, Suzuki H, Takahashi S, Yamada N, Shimano H. Kumadaki S, et al. Among authors: yamada n. J Biol Chem. 2011 Nov 25;286(47):40835-46. doi: 10.1074/jbc.M111.235283. Epub 2011 Sep 12. J Biol Chem. 2011. PMID: 21911492 Free PMC article.
Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements.
Yoshikawa T, Shimano H, Yahagi N, Ide T, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Takahashi A, Sone H, Osuga Ji J, Gotoda T, Ishibashi S, Yamada N. Yoshikawa T, et al. Among authors: yamada n. J Biol Chem. 2002 Jan 18;277(3):1705-11. doi: 10.1074/jbc.M105711200. Epub 2001 Nov 2. J Biol Chem. 2002. PMID: 11694526 Free article.
Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status.
Sone H, Shimano H, Sakakura Y, Inoue N, Amemiya-Kudo M, Yahagi N, Osawa M, Suzuki H, Yokoo T, Takahashi A, Iida K, Toyoshima H, Iwama A, Yamada N. Sone H, et al. Among authors: yamada n. Am J Physiol Endocrinol Metab. 2002 Jan;282(1):E222-30. doi: 10.1152/ajpendo.00189.2001. Am J Physiol Endocrinol Metab. 2002. PMID: 11739104 Free article.
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.
Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N. Yahagi N, et al. Among authors: yamada n. J Biol Chem. 2002 May 31;277(22):19353-7. doi: 10.1074/jbc.M201584200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923308 Free article.
Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.
Okazaki H, Osuga J, Tsukamoto K, Isoo N, Kitamine T, Tamura Y, Tomita S, Sekiya M, Yahagi N, Iizuka Y, Ohashi K, Harada K, Gotoda T, Shimano H, Kimura S, Nagai R, Yamada N, Ishibashi S. Okazaki H, et al. Among authors: yamada n. J Biol Chem. 2002 Aug 30;277(35):31893-9. doi: 10.1074/jbc.M204016200. Epub 2002 May 29. J Biol Chem. 2002. PMID: 12036961 Free article.
[Recent studies on hyperlipidemia].
Sone H, Yamada N. Sone H, et al. Among authors: yamada n. Nihon Naika Gakkai Zasshi. 2002 Apr 10;91(4):1202-7. Nihon Naika Gakkai Zasshi. 2002. PMID: 12056020 Review. Japanese. No abstract available.
3,165 results