Nettles JH - Search Results

1

Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs.

Herman BD, Schinazi RF, Zhang HW, Nettles JH, Stanton R, Detorio M, Obikhod A, Pradère U, Coats SJ, Mellors JW, Sluis-Cremer N. Herman BD, et al. Among authors: nettles jh. Nucleic Acids Res. 2012 Jan;40(1):381-90. doi: 10.1093/nar/gkr756. Epub 2011 Sep 13. Nucleic Acids Res. 2012. PMID: 21914723 Free PMC article.

2

Stanton RA, Nettles JH, Schinazi RF. Stanton RA, et al. Among authors: nettles jh. J Mol Model. 2015 Nov;21(11):282. doi: 10.1007/s00894-015-2826-7. Epub 2015 Oct 8. J Mol Model. 2015. PMID: 26450349 Free PMC article.

3

Selection and characterization of HIV-1 with a novel S68 deletion in reverse transcriptase.

Schinazi RF, Massud I, Rapp KL, Cristiano M, Detorio MA, Stanton RA, Bennett MA, Kierlin-Duncan M, Lennerstrand J, Nettles JH. Schinazi RF, et al. Among authors: nettles jh. Antimicrob Agents Chemother. 2011 May;55(5):2054-60. doi: 10.1128/AAC.01700-10. Epub 2011 Feb 28. Antimicrob Agents Chemother. 2011. PMID: 21357304 Free PMC article.

4

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides.

Zhang HW, Detorio M, Herman BD, Solomon S, Bassit L, Nettles JH, Obikhod A, Tao SJ, Mellors JW, Sluis-Cremer N, Coats SJ, Schinazi RF. Zhang HW, et al. Among authors: nettles jh. Eur J Med Chem. 2011 Sep;46(9):3832-44. doi: 10.1016/j.ejmech.2011.05.051. Epub 2011 May 30. Eur J Med Chem. 2011. PMID: 21700368 Free PMC article.

5

Discovery, characterization, and lead optimization of 7-azaindole non-nucleoside HIV-1 reverse transcriptase inhibitors.

Stanton RA, Lu X, Detorio M, Montero C, Hammond ET, Ehteshami M, Domaoal RA, Nettles JH, Feraud M, Schinazi RF. Stanton RA, et al. Among authors: nettles jh. Bioorg Med Chem Lett. 2016 Aug 15;26(16):4101-5. doi: 10.1016/j.bmcl.2016.06.065. Epub 2016 Jun 25. Bioorg Med Chem Lett. 2016. PMID: 27390064 Free PMC article.

6

Comparative analysis of in vitro processivity of HIV-1 reverse transcriptases containing mutations 65R, 74V, 184V and 65R+74V.

Sharma PL, Nettles JH, Feldman A, Rapp K, Schinazi RF. Sharma PL, et al. Among authors: nettles jh. Antiviral Res. 2009 Sep;83(3):317-23. doi: 10.1016/j.antiviral.2009.06.002. Epub 2009 Jun 23. Antiviral Res. 2009. PMID: 19555722 Free PMC article.

7

Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors.

Boucle S, Tao S, Amblard F, Stanton RA, Nettles JH, Li C, McBrayer TR, Whitaker T, Coats SJ, Schinazi RF. Boucle S, et al. Among authors: nettles jh. Bioorg Med Chem Lett. 2015 Sep 1;25(17):3711-5. doi: 10.1016/j.bmcl.2015.06.031. Epub 2015 Jun 15. Bioorg Med Chem Lett. 2015. PMID: 26099532 Free PMC article.

8

Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV.

Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen NC, North TW. Wadford DA, et al. Among authors: nettles jh. PLoS One. 2014 Jan 31;9(1):e86997. doi: 10.1371/journal.pone.0086997. eCollection 2014. PLoS One. 2014. PMID: 24498008 Free PMC article.

9

Approaches for the development of antiviral compounds: the case of hepatitis C virus.

Schinazi RF, Coats SJ, Bassit LC, Lennerstrand J, Nettles JH, Hurwitz SJ. Schinazi RF, et al. Among authors: nettles jh. Handb Exp Pharmacol. 2009;(189):25-51. doi: 10.1007/978-3-540-79086-0_2. Handb Exp Pharmacol. 2009. PMID: 19048196 Review.

10

Synthesis and evaluation of non-dimeric HCV NS5A inhibitors.

Amblard F, Zhang H, Zhou L, Shi J, Bobeck DR, Nettles JH, Chavre S, McBrayer TR, Tharnish P, Whitaker T, Coats SJ, Schinazi RF. Amblard F, et al. Among authors: nettles jh. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2031-4. doi: 10.1016/j.bmcl.2013.02.023. Epub 2013 Feb 13. Bioorg Med Chem Lett. 2013. PMID: 23466233 Free PMC article.

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