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Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.
Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, Moses HL. Ijichi H, et al. Among authors: koike k. J Clin Invest. 2011 Oct;121(10):4106-17. doi: 10.1172/JCI42754. Epub 2011 Sep 19. J Clin Invest. 2011. PMID: 21926469 Free PMC article.
Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer.
Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Kinoshita H, Nakata W, Takahashi R, Tateishi K, Tada M, Akanuma M, Yoshida H, Takeda K, Ichijo H, Omata M, Maeda S, Koike K. Hayakawa Y, et al. Among authors: koike k. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):780-5. doi: 10.1073/pnas.1011418108. Epub 2010 Dec 27. Proc Natl Acad Sci U S A. 2011. PMID: 21187402 Free PMC article.
New targeted therapies for gastric cancer.
Asaoka Y, Ikenoue T, Koike K. Asaoka Y, et al. Among authors: koike k. Expert Opin Investig Drugs. 2011 May;20(5):595-604. doi: 10.1517/13543784.2011.566863. Epub 2011 Mar 16. Expert Opin Investig Drugs. 2011. PMID: 21406037 Review.
Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway.
Kudo Y, Tanaka Y, Tateishi K, Yamamoto K, Yamamoto S, Mohri D, Isomura Y, Seto M, Nakagawa H, Asaoka Y, Tada M, Ohta M, Ijichi H, Hirata Y, Otsuka M, Ikenoue T, Maeda S, Shiina S, Yoshida H, Nakajima O, Kanai F, Omata M, Koike K. Kudo Y, et al. Among authors: koike k. J Hepatol. 2011 Dec;55(6):1400-8. doi: 10.1016/j.jhep.2011.03.025. Epub 2011 May 19. J Hepatol. 2011. PMID: 21703185
Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression.
Mohri D, Asaoka Y, Ijichi H, Miyabayashi K, Kudo Y, Seto M, Ohta M, Tada M, Tanaka Y, Ikenoue T, Tateishi K, Isayama H, Kanai F, Fukushima N, Tada M, Kawabe T, Omata M, Koike K. Mohri D, et al. Among authors: koike k. J Gastroenterol. 2012 Feb;47(2):203-13. doi: 10.1007/s00535-011-0482-y. Epub 2011 Nov 1. J Gastroenterol. 2012. PMID: 22041919
Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer.
Takahashi R, Hirata Y, Sakitani K, Nakata W, Kinoshita H, Hayakawa Y, Nakagawa H, Sakamoto K, Hikiba Y, Ijichi H, Moses HL, Maeda S, Koike K. Takahashi R, et al. Among authors: koike k. Cancer Sci. 2013 Mar;104(3):337-44. doi: 10.1111/cas.12080. Epub 2013 Jan 24. Cancer Sci. 2013. PMID: 23237571 Free PMC article.
Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα.
Yamamoto K, Tateishi K, Kudo Y, Sato T, Yamamoto S, Miyabayashi K, Matsusaka K, Asaoka Y, Ijichi H, Hirata Y, Otsuka M, Nakai Y, Isayama H, Ikenoue T, Kurokawa M, Fukayama M, Kokudo N, Omata M, Koike K. Yamamoto K, et al. Among authors: koike k. Carcinogenesis. 2014 Nov;35(11):2404-14. doi: 10.1093/carcin/bgu136. Epub 2014 Jun 19. Carcinogenesis. 2014. PMID: 24947179
3,120 results