Taylor RE - Search Results

1

Mutations in the β-tubulin binding site for peloruside A confer resistance by targeting a cleft significant in side chain binding.

Begaye A, Trostel S, Zhao Z, Taylor RE, Schriemer DC, Sackett DL. Begaye A, et al. Among authors: taylor re. Cell Cycle. 2011 Oct 1;10(19):3387-96. doi: 10.4161/cc.10.19.17706. Epub 2011 Oct 1. Cell Cycle. 2011. PMID: 21926482 Free PMC article.

2

A unique mode of microtubule stabilization induced by peloruside A.

Huzil JT, Chik JK, Slysz GW, Freedman H, Tuszynski J, Taylor RE, Sackett DL, Schriemer DC. Huzil JT, et al. Among authors: taylor re. J Mol Biol. 2008 May 16;378(5):1016-30. doi: 10.1016/j.jmb.2008.03.026. Epub 2008 Mar 19. J Mol Biol. 2008. PMID: 18405918 Free PMC article.

3

New sources of chemical diversity inspired by biosynthesis: rational design of a potent epothilone analogue.

Frein JD, Taylor RE, Sackett DL. Frein JD, et al. Among authors: taylor re. Org Lett. 2009 Aug 6;11(15):3186-9. doi: 10.1021/ol900971r. Org Lett. 2009. PMID: 19572566 Free PMC article.

4

Rapid access to conformational analogues of (+)-peloruside A.

Zhao Z, Taylor RE. Zhao Z, et al. Among authors: taylor re. Org Lett. 2012 Feb 3;14(3):669-71. doi: 10.1021/ol203268t. Epub 2012 Jan 11. Org Lett. 2012. PMID: 22235754 Free PMC article.

5

Synthesis and Biological Evaluation of 7-Deoxy-Epothilone Analogues.

Woods LM, Arico JW, Frein JD, Sackett DL, Taylor RE. Woods LM, et al. Among authors: taylor re. Int J Mol Sci. 2017 Mar 17;18(3):648. doi: 10.3390/ijms18030648. Int J Mol Sci. 2017. PMID: 28304361 Free PMC article.

6

Synthesis, conformational preferences, and biological activity of conformational analogues of the microtubule-stabilizing agents, (-)-zampanolide and (-)-dactylolide.

Henry JL, Wilson MR, Mulligan MP, Quinn TR, Sackett DL, Taylor RE. Henry JL, et al. Among authors: taylor re. Medchemcomm. 2019 Apr 9;10(5):800-805. doi: 10.1039/c9md00164f. eCollection 2019 May 1. Medchemcomm. 2019. PMID: 31191870 Free PMC article.

7

Linear (-)-Zampanolide: Flexibility in Conformation-Activity Relationships.

Umaña CA, Henry JL, Saltzman CT, Sackett DL, Jenkins LM, Taylor RE. Umaña CA, et al. Among authors: taylor re. ChemMedChem. 2023 Oct 4;18(19):e202300292. doi: 10.1002/cmdc.202300292. Epub 2023 Aug 10. ChemMedChem. 2023. PMID: 37552215 Free PMC article.

8

Total synthesis of (+)-peloruside A.

Jin M, Taylor RE. Jin M, et al. Among authors: taylor re. Org Lett. 2005 Mar 31;7(7):1303-5. doi: 10.1021/ol050070g. Org Lett. 2005. PMID: 15787492

9

Toward a total synthesis of peloruside A: enantioselective preparation of the C8-C19 region.

Taylor RE, Jin M. Taylor RE, et al. Org Lett. 2003 Dec 25;5(26):4959-61. doi: 10.1021/ol0358814. Org Lett. 2003. PMID: 14682739

10

Conformational preferences of zampanolide and dactylolide.

Larsen EM, Wilson MR, Zajicek J, Taylor RE. Larsen EM, et al. Among authors: taylor re. Org Lett. 2013 Oct 18;15(20):5246-9. doi: 10.1021/ol402462h. Epub 2013 Oct 8. Org Lett. 2013. PMID: 24102367 Free PMC article.

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