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Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.
Alavian KN, Li H, Collis L, Bonanni L, Zeng L, Sacchetti S, Lazrove E, Nabili P, Flaherty B, Graham M, Chen Y, Messerli SM, Mariggio MA, Rahner C, McNay E, Shore GC, Smith PJ, Hardwick JM, Jonas EA. Alavian KN, et al. Among authors: graham m. Nat Cell Biol. 2011 Sep 18;13(10):1224-33. doi: 10.1038/ncb2330. Nat Cell Biol. 2011. PMID: 21926988 Free PMC article.
An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore.
Alavian KN, Beutner G, Lazrove E, Sacchetti S, Park HA, Licznerski P, Li H, Nabili P, Hockensmith K, Graham M, Porter GA Jr, Jonas EA. Alavian KN, et al. Among authors: graham m. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10580-5. doi: 10.1073/pnas.1401591111. Epub 2014 Jun 16. Proc Natl Acad Sci U S A. 2014. PMID: 24979777 Free PMC article.
ATP Synthase c-Subunit Leak Causes Aberrant Cellular Metabolism in Fragile X Syndrome.
Licznerski P, Park HA, Rolyan H, Chen R, Mnatsakanyan N, Miranda P, Graham M, Wu J, Cruz-Reyes N, Mehta N, Sohail S, Salcedo J, Song E, Effman C, Effman S, Brandao L, Xu GN, Braker A, Gribkoff VK, Levy RJ, Jonas EA. Licznerski P, et al. Among authors: graham m. Cell. 2020 Sep 3;182(5):1170-1185.e9. doi: 10.1016/j.cell.2020.07.008. Epub 2020 Aug 13. Cell. 2020. PMID: 32795412 Free PMC article.
3,200 results