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Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071.
Lebois EP, Digby GJ, Sheffler DJ, Melancon BJ, Tarr JC, Cho HP, Miller NR, Morrison R, Bridges TM, Xiang Z, Daniels JS, Wood MR, Conn PJ, Lindsley CW. Lebois EP, et al. Among authors: miller nr. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6451-5. doi: 10.1016/j.bmcl.2011.08.084. Epub 2011 Aug 24. Bioorg Med Chem Lett. 2011. PMID: 21930376 Free PMC article.
Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties.
Bridges TM, Brady AE, Kennedy JP, Daniels RN, Miller NR, Kim K, Breininger ML, Gentry PR, Brogan JT, Jones CK, Conn PJ, Lindsley CW. Bridges TM, et al. Among authors: miller nr. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5439-42. doi: 10.1016/j.bmcl.2008.09.023. Epub 2008 Sep 10. Bioorg Med Chem Lett. 2008. PMID: 18805692 Free PMC article.
Diffusion tensor imaging of the optic nerve in multiple sclerosis: association with retinal damage and visual disability.
Smith SA, Williams ZR, Ratchford JN, Newsome SD, Farrell SK, Farrell JA, Gifford A, Miller NR, van Zijl PC, Calabresi PA, Reich DS. Smith SA, et al. Among authors: miller nr. AJNR Am J Neuroradiol. 2011 Oct;32(9):1662-8. doi: 10.3174/ajnr.A2574. Epub 2011 Jul 28. AJNR Am J Neuroradiol. 2011. PMID: 21799043 Free PMC article. Clinical Trial.
[No title available]
[No authors listed] [No authors listed] PMID: 37540075
553 results