Shepherd SM - Search Results

1

Pseudomonas aeruginosa 4-amino-4-deoxychorismate lyase: spatial conservation of an active site tyrosine and classification of two types of enzyme.

O'Rourke PE, Eadsforth TC, Fyfe PK, Shepherd SM, Hunter WN. O'Rourke PE, et al. Among authors: shepherd sm. PLoS One. 2011;6(9):e24158. doi: 10.1371/journal.pone.0024158. Epub 2011 Sep 15. PLoS One. 2011. PMID: 21935381 Free PMC article.

2

Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms.

Sainsbury S, Bird L, Rao V, Shepherd SM, Stuart DI, Hunter WN, Owens RJ, Ren J. Sainsbury S, et al. Among authors: shepherd sm. J Mol Biol. 2011 Jan 7;405(1):173-84. doi: 10.1016/j.jmb.2010.10.024. Epub 2010 Oct 23. J Mol Biol. 2011. PMID: 20974151 Free PMC article.

3

The structure of Serratia marcescens Lip, a membrane-bound component of the type VI secretion system.

Rao VA, Shepherd SM, English G, Coulthurst SJ, Hunter WN. Rao VA, et al. Among authors: shepherd sm. Acta Crystallogr D Biol Crystallogr. 2011 Dec;67(Pt 12):1065-72. doi: 10.1107/S0907444911046300. Epub 2011 Nov 18. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 22120744 Free PMC article.

4

Structure of Pseudomonas aeruginosa inosine 5'-monophosphate dehydrogenase.

Rao VA, Shepherd SM, Owen R, Hunter WN. Rao VA, et al. Among authors: shepherd sm. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):243-7. doi: 10.1107/S1744309113002352. Epub 2013 Feb 22. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23519796 Free PMC article.

5

Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening.

Prakash O, Führing J, Post J, Shepherd SM, Eadsforth TC, Gray D, Fedorov R, Routier FH. Prakash O, et al. Among authors: shepherd sm. Molecules. 2019 Mar 12;24(5):996. doi: 10.3390/molecules24050996. Molecules. 2019. PMID: 30871023 Free PMC article.

6

Pharmacological and structural understanding of the Trypanosoma cruzi proteasome provides key insights for developing site-specific inhibitors.

Eadsforth TC, Torrie LS, Rowland P, Edgar EV, MacLean LM, Paterson C, Robinson DA, Shepherd SM, Thomas J, Thomas MG, Gray DW, Postis VLG, De Rycker M. Eadsforth TC, et al. Among authors: shepherd sm. J Biol Chem. 2024 Dec 9;301(1):108049. doi: 10.1016/j.jbc.2024.108049. Online ahead of print. J Biol Chem. 2024. PMID: 39638245 Free PMC article.

7

Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase.

Hurtado-Guerrero R, Raimi OG, Min J, Zeng H, Vallius L, Shepherd S, Ibrahim AF, Wu H, Plotnikov AN, van Aalten DM. Hurtado-Guerrero R, et al. Biochem J. 2008 Oct 15;415(2):217-23. doi: 10.1042/BJ20081000. Biochem J. 2008. PMID: 18601654

8

Structural insights into mechanism and specificity of O-GlcNAc transferase.

Clarke AJ, Hurtado-Guerrero R, Pathak S, Schüttelkopf AW, Borodkin V, Shepherd SM, Ibrahim AF, van Aalten DM. Clarke AJ, et al. Among authors: shepherd sm. EMBO J. 2008 Oct 22;27(20):2780-8. doi: 10.1038/emboj.2008.186. Epub 2008 Sep 25. EMBO J. 2008. PMID: 18818698 Free PMC article.

9

Molecular mechanisms of yeast cell wall glucan remodeling.

Hurtado-Guerrero R, Schüttelkopf AW, Mouyna I, Ibrahim AF, Shepherd S, Fontaine T, Latgé JP, van Aalten DM. Hurtado-Guerrero R, et al. J Biol Chem. 2009 Mar 27;284(13):8461-9. doi: 10.1074/jbc.M807990200. Epub 2008 Dec 19. J Biol Chem. 2009. PMID: 19097997 Free PMC article.

10

Molecular mechanism of elongation factor 1A inhibition by a Legionella pneumophila glycosyltransferase.

Hurtado-Guerrero R, Zusman T, Pathak S, Ibrahim AF, Shepherd S, Prescott A, Segal G, van Aalten DM. Hurtado-Guerrero R, et al. Biochem J. 2010 Feb 24;426(3):281-92. doi: 10.1042/BJ20091351. Biochem J. 2010. PMID: 20030628 Free PMC article.

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