Drucker DJ - Search Results

1

Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation.

Barthson J, Germano CM, Moore F, Maida A, Drucker DJ, Marchetti P, Gysemans C, Mathieu C, Nuñez G, Jurisicova A, Eizirik DL, Gurzov EN. Barthson J, et al. Among authors: drucker dj. J Biol Chem. 2011 Nov 11;286(45):39632-43. doi: 10.1074/jbc.M111.253591. Epub 2011 Sep 21. J Biol Chem. 2011. PMID: 21937453 Free PMC article.

2

The glucagon-like peptide-1 receptor agonist oxyntomodulin enhances beta-cell function but does not inhibit gastric emptying in mice.

Maida A, Lovshin JA, Baggio LL, Drucker DJ. Maida A, et al. Among authors: drucker dj. Endocrinology. 2008 Nov;149(11):5670-8. doi: 10.1210/en.2008-0336. Epub 2008 Jul 31. Endocrinology. 2008. PMID: 18669601

3

Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for beta cell survival in mice.

Maida A, Hansotia T, Longuet C, Seino Y, Drucker DJ. Maida A, et al. Among authors: drucker dj. Gastroenterology. 2009 Dec;137(6):2146-57. doi: 10.1053/j.gastro.2009.09.004. Epub 2009 Sep 17. Gastroenterology. 2009. PMID: 19766644

4

Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-α in mice.

Maida A, Lamont BJ, Cao X, Drucker DJ. Maida A, et al. Among authors: drucker dj. Diabetologia. 2011 Feb;54(2):339-49. doi: 10.1007/s00125-010-1937-z. Epub 2010 Oct 23. Diabetologia. 2011. PMID: 20972533

5

Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice.

Bates HE, Campbell JE, Ussher JR, Baggio LL, Maida A, Seino Y, Drucker DJ. Bates HE, et al. Among authors: drucker dj. Diabetes. 2012 Jan;61(1):40-8. doi: 10.2337/db11-1060. Epub 2011 Oct 31. Diabetes. 2012. PMID: 22043004 Free PMC article.

6

Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis.

Li Y, Hansotia T, Yusta B, Ris F, Halban PA, Drucker DJ. Li Y, et al. Among authors: drucker dj. J Biol Chem. 2003 Jan 3;278(1):471-8. doi: 10.1074/jbc.M209423200. Epub 2002 Oct 29. J Biol Chem. 2003. PMID: 12409292 Free article.

7

Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure.

Hansotia T, Maida A, Flock G, Yamada Y, Tsukiyama K, Seino Y, Drucker DJ. Hansotia T, et al. Among authors: drucker dj. J Clin Invest. 2007 Jan;117(1):143-52. doi: 10.1172/JCI25483. Epub 2006 Dec 21. J Clin Invest. 2007. PMID: 17187081 Free PMC article.

8

The glucagon receptor is required for the adaptive metabolic response to fasting.

Longuet C, Sinclair EM, Maida A, Baggio LL, Maziarz M, Charron MJ, Drucker DJ. Longuet C, et al. Among authors: drucker dj. Cell Metab. 2008 Nov;8(5):359-71. doi: 10.1016/j.cmet.2008.09.008. Cell Metab. 2008. PMID: 19046568 Free PMC article.

9

Glucagon-like peptide-2 increases intestinal lipid absorption and chylomicron production via CD36.

Hsieh J, Longuet C, Maida A, Bahrami J, Xu E, Baker CL, Brubaker PL, Drucker DJ, Adeli K. Hsieh J, et al. Among authors: drucker dj. Gastroenterology. 2009 Sep;137(3):997-1005, 1005.e1-4. doi: 10.1053/j.gastro.2009.05.051. Epub 2009 May 29. Gastroenterology. 2009. PMID: 19482026

10

Glucagon gene transcription in an islet cell line is regulated via a protein kinase C-activated pathway.

Philippe J, Drucker DJ, Habener JF. Philippe J, et al. Among authors: drucker dj. J Biol Chem. 1987 Feb 5;262(4):1823-8. J Biol Chem. 1987. PMID: 2879843 Free article.

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