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Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkappaB.
Wang C, Chen T, Zhang N, Yang M, Li B, Lü X, Cao X, Ling C. Wang C, et al. Among authors: yang m. J Biol Chem. 2009 Feb 6;284(6):3804-13. doi: 10.1074/jbc.M807191200. Epub 2008 Dec 12. J Biol Chem. 2009. Retraction in: J Biol Chem. 2021 Jan-Jun;296:100767. doi: 10.1016/j.jbc.2021.100767 PMID: 19074436 Free article. Retracted.
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