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The Lin28/let-7 axis regulates glucose metabolism.
Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI; DIAGRAM Consortium; MAGIC Investigators; Altshuler D, Daley GQ. Zhu H, et al. Among authors: hagan jp. Cell. 2011 Sep 30;147(1):81-94. doi: 10.1016/j.cell.2011.08.033. Cell. 2011. PMID: 21962509 Free PMC article.
Lin28a regulates germ cell pool size and fertility.
Shinoda G, De Soysa TY, Seligson MT, Yabuuchi A, Fujiwara Y, Huang PY, Hagan JP, Gregory RI, Moss EG, Daley GQ. Shinoda G, et al. Among authors: hagan jp. Stem Cells. 2013 May;31(5):1001-9. doi: 10.1002/stem.1343. Stem Cells. 2013. PMID: 23378032 Free PMC article.
The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
Northcott PA, Fernandez-L A, Hagan JP, Ellison DW, Grajkowska W, Gillespie Y, Grundy R, Van Meter T, Rutka JT, Croce CM, Kenney AM, Taylor MD. Northcott PA, et al. Among authors: hagan jp. Cancer Res. 2009 Apr 15;69(8):3249-55. doi: 10.1158/0008-5472.CAN-08-4710. Epub 2009 Apr 7. Cancer Res. 2009. PMID: 19351822 Free PMC article.
The LIN28/let-7 Pathway in Cancer.
Balzeau J, Menezes MR, Cao S, Hagan JP. Balzeau J, et al. Among authors: hagan jp. Front Genet. 2017 Mar 28;8:31. doi: 10.3389/fgene.2017.00031. eCollection 2017. Front Genet. 2017. PMID: 28400788 Free PMC article. Review.
Fluid shear stress activates YAP1 to promote cancer cell motility.
Lee HJ, Diaz MF, Price KM, Ozuna JA, Zhang S, Sevick-Muraca EM, Hagan JP, Wenzel PL. Lee HJ, et al. Among authors: hagan jp. Nat Commun. 2017 Jan 18;8:14122. doi: 10.1038/ncomms14122. Nat Commun. 2017. PMID: 28098159 Free PMC article.
E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Chong JL, Wenzel PL, Sáenz-Robles MT, Nair V, Ferrey A, Hagan JP, Gomez YM, Sharma N, Chen HZ, Ouseph M, Wang SH, Trikha P, Culp B, Mezache L, Winton DJ, Sansom OJ, Chen D, Bremner R, Cantalupo PG, Robinson ML, Pipas JM, Leone G. Chong JL, et al. Among authors: hagan jp. Nature. 2009 Dec 17;462(7275):930-4. doi: 10.1038/nature08677. Nature. 2009. PMID: 20016602 Free PMC article.
54 results