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A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis.
Varadarajan N, Julg B, Yamanaka YJ, Chen H, Ogunniyi AO, McAndrew E, Porter LC, Piechocka-Trocha A, Hill BJ, Douek DC, Pereyra F, Walker BD, Love JC. Varadarajan N, et al. Among authors: walker bd. J Clin Invest. 2011 Nov;121(11):4322-31. doi: 10.1172/JCI58653. Epub 2011 Oct 3. J Clin Invest. 2011. PMID: 21965332 Free PMC article.
Lack of strong immune selection pressure by the immunodominant, HLA-A*0201-restricted cytotoxic T lymphocyte response in chronic human immunodeficiency virus-1 infection.
Brander C, Hartman KE, Trocha AK, Jones NG, Johnson RP, Korber B, Wentworth P, Buchbinder SP, Wolinsky S, Walker BD, Kalams SA. Brander C, et al. Among authors: walker bd. J Clin Invest. 1998 Jun 1;101(11):2559-66. doi: 10.1172/JCI2405. J Clin Invest. 1998. PMID: 9616227 Free PMC article.
De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection.
Allen TM, Yu XG, Kalife ET, Reyor LL, Lichterfeld M, John M, Cheng M, Allgaier RL, Mui S, Frahm N, Alter G, Brown NV, Johnston MN, Rosenberg ES, Mallal SA, Brander C, Walker BD, Altfeld M. Allen TM, et al. Among authors: walker bd. J Virol. 2005 Oct;79(20):12952-60. doi: 10.1128/JVI.79.20.12952-12960.2005. J Virol. 2005. PMID: 16188997 Free PMC article.
Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes.
Yu XG, Lichterfeld M, Chetty S, Williams KL, Mui SK, Miura T, Frahm N, Feeney ME, Tang Y, Pereyra F, Labute MX, Pfafferott K, Leslie A, Crawford H, Allgaier R, Hildebrand W, Kaslow R, Brander C, Allen TM, Rosenberg ES, Kiepiela P, Vajpayee M, Goepfert PA, Altfeld M, Goulder PJ, Walker BD. Yu XG, et al. Among authors: walker bd. J Virol. 2007 Feb;81(4):1619-31. doi: 10.1128/JVI.01580-06. Epub 2006 Nov 22. J Virol. 2007. PMID: 17121793 Free PMC article.
Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes.
Honeyborne I, Prendergast A, Pereyra F, Leslie A, Crawford H, Payne R, Reddy S, Bishop K, Moodley E, Nair K, van der Stok M, McCarthy N, Rousseau CM, Addo M, Mullins JI, Brander C, Kiepiela P, Walker BD, Goulder PJ. Honeyborne I, et al. Among authors: walker bd. J Virol. 2007 Apr;81(7):3667-72. doi: 10.1128/JVI.02689-06. Epub 2007 Jan 24. J Virol. 2007. PMID: 17251285 Free PMC article.
Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction.
Kaufmann DE, Kavanagh DG, Pereyra F, Zaunders JJ, Mackey EW, Miura T, Palmer S, Brockman M, Rathod A, Piechocka-Trocha A, Baker B, Zhu B, Le Gall S, Waring MT, Ahern R, Moss K, Kelleher AD, Coffin JM, Freeman GJ, Rosenberg ES, Walker BD. Kaufmann DE, et al. Among authors: walker bd. Nat Immunol. 2007 Nov;8(11):1246-54. doi: 10.1038/ni1515. Epub 2007 Sep 30. Nat Immunol. 2007. PMID: 17906628
674 results