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Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration.
Rowan S, Jiang S, Korem T, Szymanski J, Chang ML, Szelog J, Cassalman C, Dasuri K, McGuire C, Nagai R, Du XL, Brownlee M, Rabbani N, Thornalley PJ, Baleja JD, Deik AA, Pierce KA, Scott JM, Clish CB, Smith DE, Weinberger A, Avnit-Sagi T, Lotan-Pompan M, Segal E, Taylor A. Rowan S, et al. Among authors: brownlee m. Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4472-E4481. doi: 10.1073/pnas.1702302114. Epub 2017 May 15. Proc Natl Acad Sci U S A. 2017. PMID: 28507131 Free PMC article.
Negative consequences of glycation.
Brownlee M. Brownlee M. Metabolism. 2000 Feb;49(2 Suppl 1):9-13. doi: 10.1016/s0026-0495(00)80078-5. Metabolism. 2000. PMID: 10693913 Review.
Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans.
Morcos M, Du X, Pfisterer F, Hutter H, Sayed AA, Thornalley P, Ahmed N, Baynes J, Thorpe S, Kukudov G, Schlotterer A, Bozorgmehr F, El Baki RA, Stern D, Moehrlen F, Ibrahim Y, Oikonomou D, Hamann A, Becker C, Zeier M, Schwenger V, Miftari N, Humpert P, Hammes HP, Buechler M, Bierhaus A, Brownlee M, Nawroth PP. Morcos M, et al. Among authors: brownlee m. Aging Cell. 2008 Mar;7(2):260-9. doi: 10.1111/j.1474-9726.2008.00371.x. Epub 2008 Jan 21. Aging Cell. 2008. PMID: 18221415 Free article.
Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription.
Yao D, Taguchi T, Matsumura T, Pestell R, Edelstein D, Giardino I, Suske G, Ahmed N, Thornalley PJ, Sarthy VP, Hammes HP, Brownlee M. Yao D, et al. Among authors: brownlee m. Cell. 2006 Jan 27;124(2):275-86. doi: 10.1016/j.cell.2005.11.024. Epub 2006 Jan 12. Cell. 2006. Retraction in: Cell. 2007 Feb 9;128(3):625. doi: 10.1016/j.cell.2007.01.026 PMID: 16413606 Free article. Retracted.
Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin-treated, apolipoprotein E-deficient mice.
Geoffrion M, Du X, Irshad Z, Vanderhyden BC, Courville K, Sui G, D'Agati VD, Ott-Braschi S, Rabbani N, Thornalley PJ, Brownlee M, Milne RW. Geoffrion M, et al. Among authors: brownlee m. Physiol Rep. 2014 Jun 11;2(6):e12043. doi: 10.14814/phy2.12043. Print 2014 Jun 1. Physiol Rep. 2014. PMID: 24920125 Free PMC article.
236 results