Zhuang XM - Search Results

1

Metabolism of novel anti-HIV agent 3-cyanomethyl-4-methyl-DCK by human liver microsomes and recombinant CYP enzymes.

Zhuang XM, Deng JT, Li H, Kong WL, Ruan JX, Xie L. Zhuang XM, et al. Acta Pharmacol Sin. 2011 Oct;32(10):1276-84. doi: 10.1038/aps.2011.91. Acta Pharmacol Sin. 2011. PMID: 21970838 Free PMC article.

2

A simplified model to predict P-glycoprotein interacting drugs from 3D molecular interaction field.

Zhuang XM, Xiao JH, Li JT, Zhang ZQ, Ruan JX. Zhuang XM, et al. Int J Pharm. 2006 Feb 17;309(1-2):109-14. doi: 10.1016/j.ijpharm.2005.11.009. Epub 2005 Dec 20. Int J Pharm. 2006. PMID: 16376035

3

Development and preclinical studies of broad-spectrum anti-HIV agent (3'R,4'R)-3-cyanomethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (3-cyanomethyl-4-methyl-DCK).

Xie L, Guo HF, Lu H, Zhuang XM, Zhang AM, Wu G, Ruan JX, Zhou T, Yu D, Qian K, Lee KH, Jiang S. Xie L, et al. Among authors: zhuang xm. J Med Chem. 2008 Dec 25;51(24):7689-96. doi: 10.1021/jm8003009. J Med Chem. 2008. PMID: 19053755 Free PMC article.

4

[In vitro comparison of thienorphine metabolism in liver microsomes of human, Beagle dog and rat].

Deng JT, Zhuang XM, Li H. Deng JT, et al. Among authors: zhuang xm. Yao Xue Xue Bao. 2010 Jan;45(1):98-103. Yao Xue Xue Bao. 2010. PMID: 21351457 Chinese.

5

[In vitro O-demethylation of rotundine by recombinant human CYP isoenzymes].

Li CZ, Lin QH, Zhuang XM, Xie JW, Li H. Li CZ, et al. Among authors: zhuang xm. Yao Xue Xue Bao. 2010 Mar;45(3):307-13. Yao Xue Xue Bao. 2010. PMID: 21351505 Chinese.

6

[Metabolism of 3-cyanomethyl-4-methyl-DCK, a new anti-HIV candidate, in human intestinal microsomes].

Zhuang XM, Wen YY, Li H, Deng JT, Kong WL, Tian XT, Cui SL, Xie L. Zhuang XM, et al. Yao Xue Xue Bao. 2010 Sep;45(9):1116-22. Yao Xue Xue Bao. 2010. PMID: 21351567 Chinese.

7

[Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].

Shen GL, Zhuang XM, Yuan M, Sun HX, Li H. Shen GL, et al. Among authors: zhuang xm. Yao Xue Xue Bao. 2012 Apr;47(4):459-65. Yao Xue Xue Bao. 2012. PMID: 22799027 Chinese.

8

Pre-column derivatization combined with UHPLC-MS/MS for rapid and sensitive quantification of bakuchiol in rat plasma.

Zhuang X, Zhong Y, Yuan M, Li H. Zhuang X, et al. J Pharm Biomed Anal. 2013 Mar 5;75:18-24. doi: 10.1016/j.jpba.2012.11.001. Epub 2012 Nov 10. J Pharm Biomed Anal. 2013. PMID: 23312380

9

Prodrug design, synthesis and pharmacokinetic evaluation of (3' R, 4' R)-3-hydroxymethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone.

Guo H, Zhuang X, Qian K, Sun L, Wang X, Li H, Lee K, Xie L. Guo H, et al. Acta Pharm Sin B. 2012 Apr 1;2(2):213-219. doi: 10.1016/j.apsb.2012.02.008. Acta Pharm Sin B. 2012. PMID: 23687633 Free PMC article.

10

Identification and characterization of psoralen and isopsoralen as potent CYP1A2 reversible and time-dependent inhibitors in human and rat preclinical studies.

Zhuang XM, Zhong YH, Xiao WB, Li H, Lu C. Zhuang XM, et al. Drug Metab Dispos. 2013 Nov;41(11):1914-22. doi: 10.1124/dmd.113.053199. Epub 2013 Aug 23. Drug Metab Dispos. 2013. PMID: 23975028

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