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D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation.
Juang SH, Lung CC, Hsu PC, Hsu KS, Li YC, Hong PC, Shiah HS, Kuo CC, Huang CW, Wang YC, Huang L, Chen TS, Chen SF, Fu KC, Hsu CL, Lin MJ, Chang CJ, Ashendel CL, Chan TC, Chou KM, Chang JY. Juang SH, et al. Among authors: chang jy, chang cj. Mol Cancer Ther. 2007 Jan;6(1):193-202. doi: 10.1158/1535-7163.MCT-06-0482. Mol Cancer Ther. 2007. PMID: 17237279
A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule.
Liou JP, Hsu KS, Kuo CC, Chang CY, Chang JY. Liou JP, et al. Among authors: chang jy, chang cy. J Pharmacol Exp Ther. 2007 Oct;323(1):398-405. doi: 10.1124/jpet.107.126680. Epub 2007 Jul 27. J Pharmacol Exp Ther. 2007. PMID: 17660383
Investigations of survivin: the past, present and future.
Cheung CH, Cheng L, Chang KY, Chen HH, Chang JY. Cheung CH, et al. Among authors: chang jy, chang ky. Front Biosci (Landmark Ed). 2011 Jan 1;16(3):952-61. doi: 10.2741/3728. Front Biosci (Landmark Ed). 2011. PMID: 21196211 Free article. Review.
1,798 results