Ibrahim TS - Search Results

1

Design, synthesis, and biological activity of a novel series of 2,5-disubstituted furans/pyrroles as HIV-1 fusion inhibitors targeting gp41.

Jiang S, Tala SR, Lu H, Zou P, Avan I, Ibrahim TS, Abo-Dya NE, Abdelmajeid A, Debnath AK, Katritzky AR. Jiang S, et al. Among authors: ibrahim ts. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6895-8. doi: 10.1016/j.bmcl.2011.08.081. Epub 2011 Sep 5. Bioorg Med Chem Lett. 2011. PMID: 21978673

2

Chemical ligation of S-scylated cysteine peptides to form native peptides via 5-, 11-, and 14-membered cyclic transition states.

Katritzky AR, Tala SR, Abo-Dya NE, Ibrahim TS, El-Feky SA, Gyanda K, Pandya KM. Katritzky AR, et al. Among authors: ibrahim ts. J Org Chem. 2011 Jan 7;76(1):85-96. doi: 10.1021/jo1015757. Epub 2010 Dec 15. J Org Chem. 2011. PMID: 21158395

3

Cysteinoyl- and cysteine-containing dipeptidoylbenzotriazoles with free sulfhydryl groups: easy access to N-terminal and internal cysteine peptides.

Ibrahim TS, Tala SR, El-Feky SA, Abdel-Samii ZK, Katritzky AR. Ibrahim TS, et al. Chem Biol Drug Des. 2012 Aug;80(2):194-202. doi: 10.1111/j.1747-0285.2011.01303.x. Epub 2012 May 14. Chem Biol Drug Des. 2012. PMID: 22177655

4

Benzotriazole-Mediated Synthesis and Antibacterial Activity of Novel N-Acylcephalexins.

Agha KA, Abo-Dya NE, Ibrahim TS, Abdel-Aal EH, Hegazy WA. Agha KA, et al. Among authors: ibrahim ts. Sci Pharm. 2016 Apr 13;84(3):484-496. doi: 10.3390/scipharm84030484. Sci Pharm. 2016. PMID: 28117314 Free PMC article.

5

Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors.

Ibrahim TS, Bokhtia RM, Al-Mahmoudy AMM, Taher ES, AlAwadh MA, Elagawany M, Abdel-Aal EH, Panda S, Gouda AM, Asfour HZ, Alhakamy NA, Youssif BGM. Ibrahim TS, et al. Bioorg Chem. 2020 Jun;99:103782. doi: 10.1016/j.bioorg.2020.103782. Epub 2020 Mar 24. Bioorg Chem. 2020. PMID: 32229348

6

Design, synthesis and anticancer activity of novel valproic acid conjugates with improved histone deacetylase (HDAC) inhibitory activity.

Ibrahim TS, Sheha TA, Abo-Dya NE, AlAwadh MA, Alhakamy NA, Abdel-Samii ZK, Panda SS, Abuo-Rahma GEA, Mohamed MFA. Ibrahim TS, et al. Bioorg Chem. 2020 Jun;99:103797. doi: 10.1016/j.bioorg.2020.103797. Epub 2020 Mar 30. Bioorg Chem. 2020. PMID: 32247939

7

Design, synthesis and pharmacological screening of novel renoprotective methionine-based peptidomimetics: Amelioration of cisplatin-induced nephrotoxicity.

Agha KA, Ibrahim TS, Elsherbiny NM, El-Sherbiny M, Abdel-Aal EH, Abdel-Samii ZK, Abo-Dya NE. Agha KA, et al. Among authors: ibrahim ts. Bioorg Chem. 2021 Sep;114:105100. doi: 10.1016/j.bioorg.2021.105100. Epub 2021 Jun 17. Bioorg Chem. 2021. PMID: 34246972

8

Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening.

Agha KA, Abo-Dya NE, Issahaku AR, Agoni C, Soliman MES, Abdel-Aal EH, Abdel-Samii ZK, Ibrahim TS. Agha KA, et al. Among authors: ibrahim ts. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1241-1256. doi: 10.1080/14756366.2022.2068147. J Enzyme Inhib Med Chem. 2022. PMID: 35484855 Free PMC article.

9

Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold.

Ibrahim TS, Salem IM, Mostafa SM, El-Sabbagh OI, ElKhamisi MKM, Hegazy L, Elgendy B. Ibrahim TS, et al. Bioorg Chem. 2020 Jul;100:103878. doi: 10.1016/j.bioorg.2020.103878. Epub 2020 Apr 26. Bioorg Chem. 2020. PMID: 32361486

10

Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.

Ibrahim TS, Hawwas MM, Taher ES, Alhakamy NA, Alfaleh MA, Elagawany M, Elgendy B, Zayed GM, Mohamed MFA, Abdel-Samii ZK, Elshaier YAMM. Ibrahim TS, et al. Bioorg Chem. 2020 Dec;105:104352. doi: 10.1016/j.bioorg.2020.104352. Epub 2020 Oct 8. Bioorg Chem. 2020. PMID: 33080494

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