Lu H - Search Results

1

Design, synthesis, and biological activity of a novel series of 2,5-disubstituted furans/pyrroles as HIV-1 fusion inhibitors targeting gp41.

Jiang S, Tala SR, Lu H, Zou P, Avan I, Ibrahim TS, Abo-Dya NE, Abdelmajeid A, Debnath AK, Katritzky AR. Jiang S, et al. Among authors: lu h. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6895-8. doi: 10.1016/j.bmcl.2011.08.081. Epub 2011 Sep 5. Bioorg Med Chem Lett. 2011. PMID: 21978673

2

Conserved salt bridge between the N- and C-terminal heptad repeat regions of the human immunodeficiency virus type 1 gp41 core structure is critical for virus entry and inhibition.

He Y, Liu S, Li J, Lu H, Qi Z, Liu Z, Debnath AK, Jiang S. He Y, et al. Among authors: lu h. J Virol. 2008 Nov;82(22):11129-39. doi: 10.1128/JVI.01060-08. Epub 2008 Sep 3. J Virol. 2008. PMID: 18768964 Free PMC article.

3

Design, synthesis, and structure-activity relationship of a novel series of 2-aryl 5-(4-oxo-3-phenethyl-2-thioxothiazolidinylidenemethyl)furans as HIV-1 entry inhibitors.

Katritzky AR, Tala SR, Lu H, Vakulenko AV, Chen QY, Sivapackiam J, Pandya K, Jiang S, Debnath AK. Katritzky AR, et al. Among authors: lu h. J Med Chem. 2009 Dec 10;52(23):7631-9. doi: 10.1021/jm900450n. J Med Chem. 2009. PMID: 19746983 Free PMC article.

4

Structure-based design, synthesis and biological evaluation of new N-carboxyphenylpyrrole derivatives as HIV fusion inhibitors targeting gp41.

Wang Y, Lu H, Zhu Q, Jiang S, Liao Y. Wang Y, et al. Among authors: lu h. Bioorg Med Chem Lett. 2010 Jan 1;20(1):189-92. doi: 10.1016/j.bmcl.2009.10.139. Epub 2009 Nov 5. Bioorg Med Chem Lett. 2010. PMID: 19932616 Free PMC article.

5

Design, synthesis, and biological activity of novel 5-((arylfuran/1H-pyrrol-2-yl)methylene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-ones as HIV-1 fusion inhibitors targeting gp41.

Jiang S, Tala SR, Lu H, Abo-Dya NE, Avan I, Gyanda K, Lu L, Katritzky AR, Debnath AK. Jiang S, et al. Among authors: lu h, lu l. J Med Chem. 2011 Jan 27;54(2):572-9. doi: 10.1021/jm101014v. Epub 2010 Dec 29. J Med Chem. 2011. PMID: 21190369

6

A novel chimeric protein-based HIV-1 fusion inhibitor targeting gp41 glycoprotein with high potency and stability.

Pan C, Cai L, Lu H, Lu L, Jiang S. Pan C, et al. Among authors: lu h, lu l. J Biol Chem. 2011 Aug 12;286(32):28425-34. doi: 10.1074/jbc.M111.241992. Epub 2011 Jun 20. J Biol Chem. 2011. PMID: 21690094 Free PMC article.

7

Rapid and automated fluorescence-linked immunosorbent assay for high-throughput screening of HIV-1 fusion inhibitors targeting gp41.

Liu S, Boyer-Chatenet L, Lu H, Jiang S. Liu S, et al. Among authors: lu h. J Biomol Screen. 2003 Dec;8(6):685-93. doi: 10.1177/1087057103259155. J Biomol Screen. 2003. PMID: 14711394

8

N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion.

Jiang S, Lu H, Liu S, Zhao Q, He Y, Debnath AK. Jiang S, et al. Among authors: lu h. Antimicrob Agents Chemother. 2004 Nov;48(11):4349-59. doi: 10.1128/AAC.48.11.4349-4359.2004. Antimicrob Agents Chemother. 2004. PMID: 15504864 Free PMC article.

9

Different from the HIV fusion inhibitor C34, the anti-HIV drug Fuzeon (T-20) inhibits HIV-1 entry by targeting multiple sites in gp41 and gp120.

Liu S, Lu H, Niu J, Xu Y, Wu S, Jiang S. Liu S, et al. Among authors: lu h. J Biol Chem. 2005 Mar 25;280(12):11259-73. doi: 10.1074/jbc.M411141200. Epub 2005 Jan 7. J Biol Chem. 2005. PMID: 15640162 Free article.

10

Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41.

Liu S, Lu H, Zhao Q, He Y, Niu J, Debnath AK, Wu S, Jiang S. Liu S, et al. Among authors: lu h. Biochim Biophys Acta. 2005 May 25;1723(1-3):270-81. doi: 10.1016/j.bbagen.2005.02.012. Epub 2005 Mar 24. Biochim Biophys Acta. 2005. PMID: 15823507

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

23,282 results

Search Page

Filters