Gormley JA - Search Results

1

The role of Cathepsin S as a marker of prognosis and predictor of chemotherapy benefit in adjuvant CRC: a pilot study.

Gormley JA, Hegarty SM, O'Grady A, Stevenson MR, Burden RE, Barrett HL, Scott CJ, Johnston JA, Wilson RH, Kay EW, Johnston PG, Olwill SA. Gormley JA, et al. Br J Cancer. 2011 Nov 8;105(10):1487-94. doi: 10.1038/bjc.2011.408. Epub 2011 Oct 11. Br J Cancer. 2011. PMID: 21989182 Free PMC article. Clinical Trial.

2

Inhibition of Cathepsin S by Fsn0503 enhances the efficacy of chemotherapy in colorectal carcinomas.

Burden RE, Gormley JA, Kuehn D, Ward C, Kwok HF, Gazdoiu M, McClurg A, Jaquin TJ, Johnston JA, Scott CJ, Olwill SA. Burden RE, et al. Among authors: gormley ja. Biochimie. 2012 Feb;94(2):487-93. doi: 10.1016/j.biochi.2011.08.017. Epub 2011 Aug 31. Biochimie. 2012. PMID: 21896304

3

Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis.

Burden RE, Gormley JA, Jaquin TJ, Small DM, Quinn DJ, Hegarty SM, Ward C, Walker B, Johnston JA, Olwill SA, Scott CJ. Burden RE, et al. Among authors: gormley ja. Clin Cancer Res. 2009 Oct 1;15(19):6042-51. doi: 10.1158/1078-0432.CCR-09-1262. Epub 2009 Sep 29. Clin Cancer Res. 2009. PMID: 19789302

4

Antibody targeting of cathepsin S inhibits angiogenesis and synergistically enhances anti-VEGF.

Ward C, Kuehn D, Burden RE, Gormley JA, Jaquin TJ, Gazdoiu M, Small D, Bicknell R, Johnston JA, Scott CJ, Olwill SA. Ward C, et al. Among authors: gormley ja. PLoS One. 2010 Sep 2;5(9):e12543. doi: 10.1371/journal.pone.0012543. PLoS One. 2010. PMID: 20824056 Free PMC article.

5

Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity.

Kwok HF, Buick RJ, Kuehn D, Gormley JA, Doherty D, Jaquin TJ, McClurg A, Ward C, Byrne T, Jaworski J, Leung KL, Snoddy P, McAnally C, Burden RE, Gray B, Lowry J, Sermadiras I, Gruszka N, Courtenay-Luck N, Kissenpfennig A, Scott CJ, Johnston JA, Olwill SA. Kwok HF, et al. Among authors: gormley ja. Mol Cancer. 2011 Dec 14;10:147. doi: 10.1186/1476-4598-10-147. Mol Cancer. 2011. PMID: 22168338 Free PMC article.

6

A Novel High-Throughput Technique for Identifying Monoclonal Antibodies Capable of Death Receptor Induced Apoptosis.

Kwok HF, Gormley JA, Scott CJ, Johnston JA, Olwill SA. Kwok HF, et al. Among authors: gormley ja. J Cell Death. 2009 Dec 2;2:45-51. doi: 10.4137/jcd.s3660. eCollection 2009. J Cell Death. 2009. PMID: 26124680 Free PMC article.

7

Enhanced antitumor activity of the photosensitizer meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate through encapsulation in antibody-targeted chitosan/alginate nanoparticles.

Abdelghany SM, Schmid D, Deacon J, Jaworski J, Fay F, McLaughlin KM, Gormley JA, Burrows JF, Longley DB, Donnelly RF, Scott CJ. Abdelghany SM, et al. Among authors: gormley ja. Biomacromolecules. 2013 Feb 11;14(2):302-10. doi: 10.1021/bm301858a. Epub 2013 Jan 31. Biomacromolecules. 2013. PMID: 23327610 Free PMC article.

8

Fsn0503h antibody-mediated blockade of cathepsin S as a potential therapeutic strategy for the treatment of solid tumors.

Vázquez R, Astorgues-Xerri L, Bekradda M, Gormley J, Buick R, Kerr P, Cvitkovic E, Raymond E, D'Incalci M, Frapolli R, Riveiro ME. Vázquez R, et al. Biochimie. 2015 Jan;108:101-7. doi: 10.1016/j.biochi.2014.10.025. Epub 2014 Nov 5. Biochimie. 2015. PMID: 25446656

9

Targeting Adrenomedullin in Oncology: A Feasible Strategy With Potential as Much More Than an Alternative Anti-Angiogenic Therapy.

Vázquez R, Riveiro ME, Berenguer-Daizé C, O'Kane A, Gormley J, Touzelet O, Rezai K, Bekradda M, Ouafik L. Vázquez R, et al. Front Oncol. 2021 Jan 6;10:589218. doi: 10.3389/fonc.2020.589218. eCollection 2020. Front Oncol. 2021. PMID: 33489885 Free PMC article. Review.

10

Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6.

Chrencik JE, Patny A, Leung IK, Korniski B, Emmons TL, Hall T, Weinberg RA, Gormley JA, Williams JM, Day JE, Hirsch JL, Kiefer JR, Leone JW, Fischer HD, Sommers CD, Huang HC, Jacobsen EJ, Tenbrink RE, Tomasselli AG, Benson TE. Chrencik JE, et al. Among authors: gormley ja. J Mol Biol. 2010 Jul 16;400(3):413-33. doi: 10.1016/j.jmb.2010.05.020. Epub 2010 May 15. J Mol Biol. 2010. PMID: 20478313

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