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MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals.
Marampon F, Gravina GL, Di Rocco A, Bonfili P, Di Staso M, Fardella C, Polidoro L, Ciccarelli C, Festuccia C, Popov VM, Pestell RG, Tombolini V, Zani BM. Marampon F, et al. Among authors: pestell rg. Mol Cancer Ther. 2011 Jan;10(1):159-68. doi: 10.1158/1535-7163.MCT-10-0631. Mol Cancer Ther. 2011. PMID: 21220498 Free PMC article.
Testosterone-mediated activation of androgenic signalling sustains in vitro the transformed and radioresistant phenotype of rhabdomyosarcoma cell lines.
Giannattasio S, Megiorni F, Di Nisio V, Del Fattore A, Fontanella R, Camero S, Antinozzi C, Festuccia C, Gravina GL, Cecconi S, Dominici C, Di Luigi L, Ciccarelli C, De Cesaris P, Riccioli A, Zani BM, Lenzi A, Pestell RG, Filippini A, Crescioli C, Tombolini V, Marampon F. Giannattasio S, et al. Among authors: pestell rg. J Endocrinol Invest. 2019 Feb;42(2):183-197. doi: 10.1007/s40618-018-0900-6. Epub 2018 May 22. J Endocrinol Invest. 2019. PMID: 29790086
Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage.
Marampon F, Gravina G, Ju X, Vetuschi A, Sferra R, Casimiro M, Pompili S, Festuccia C, Colapietro A, Gaudio E, Di Cesare E, Tombolini V, Pestell RG. Marampon F, et al. Among authors: pestell rg. Oncotarget. 2016 Feb 2;7(5):5383-400. doi: 10.18632/oncotarget.6579. Oncotarget. 2016. PMID: 26689991 Free PMC article.
The Dachshund gene in development and hormone-responsive tumorigenesis.
Popov VM, Wu K, Zhou J, Powell MJ, Mardon G, Wang C, Pestell RG. Popov VM, et al. Among authors: pestell rg. Trends Endocrinol Metab. 2010 Jan;21(1):41-9. doi: 10.1016/j.tem.2009.08.002. Epub 2009 Nov 5. Trends Endocrinol Metab. 2010. PMID: 19896866 Free PMC article. Review.
493 results