Atkins WM - Search Results

1

The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4.

Roberts AG, Yang J, Halpert JR, Nelson SD, Thummel KT, Atkins WM. Roberts AG, et al. Among authors: atkins wm. Biochemistry. 2011 Dec 20;50(50):10804-18. doi: 10.1021/bi200924t. Epub 2011 Nov 22. Biochemistry. 2011. PMID: 21992114 Free PMC article.

2

Glutathione S-transferase catalyzes the isomerization of (R)-2-hydroxymenthofuran to mintlactones.

Khojasteh-Bakht SC, Nelson SD, Atkins WM. Khojasteh-Bakht SC, et al. Among authors: atkins wm. Arch Biochem Biophys. 1999 Oct 1;370(1):59-65. doi: 10.1006/abbi.1999.1361. Arch Biochem Biophys. 1999. PMID: 10496977

3

The thermodynamic landscape of testosterone binding to cytochrome P450 3A4: ligand binding and spin state equilibria.

Roberts AG, Campbell AP, Atkins WM. Roberts AG, et al. Among authors: atkins wm. Biochemistry. 2005 Feb 1;44(4):1353-66. doi: 10.1021/bi0481390. Biochemistry. 2005. PMID: 15667229

4

Fluorescent photoaffinity labeling of cytochrome P450 3A4 by lapachenole: identification of modification sites by mass spectrometry.

Wen B, Doneanu CE, Gartner CA, Roberts AG, Atkins WM, Nelson SD. Wen B, et al. Among authors: atkins wm. Biochemistry. 2005 Feb 15;44(6):1833-45. doi: 10.1021/bi048228c. Biochemistry. 2005. PMID: 15697209

5

Probing the CYP3A4 active site by cysteine scanning mutagenesis and photoaffinity labeling.

Wen B, Doneanu CE, Lampe JN, Roberts AG, Atkins WM, Nelson SD. Wen B, et al. Among authors: atkins wm. Arch Biochem Biophys. 2005 Dec 15;444(2):100-11. doi: 10.1016/j.abb.2005.09.010. Epub 2005 Oct 21. Arch Biochem Biophys. 2005. PMID: 16289363

6

NMR studies of ligand binding to P450(eryF) provides insight into the mechanism of cooperativity.

Roberts AG, Díaz MD, Lampe JN, Shireman LM, Grinstead JS, Dabrowski MJ, Pearson JT, Bowman MK, Atkins WM, Campbell AP. Roberts AG, et al. Among authors: atkins wm. Biochemistry. 2006 Feb 14;45(6):1673-84. doi: 10.1021/bi0518895. Biochemistry. 2006. PMID: 16460014

7

Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase.

Wen B, Lampe JN, Roberts AG, Atkins WM, David Rodrigues A, Nelson SD. Wen B, et al. Among authors: atkins wm. Arch Biochem Biophys. 2006 Oct 1;454(1):42-54. doi: 10.1016/j.abb.2006.08.003. Epub 2006 Aug 22. Arch Biochem Biophys. 2006. PMID: 16959210 Free PMC article.

8

Time-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4.

Lampe JN, Atkins WM. Lampe JN, et al. Among authors: atkins wm. Biochemistry. 2006 Oct 10;45(40):12204-15. doi: 10.1021/bi060083h. Biochemistry. 2006. PMID: 17014074

9

Energetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4.

Roberts AG, Atkins WM. Roberts AG, et al. Among authors: atkins wm. Arch Biochem Biophys. 2007 Jul 1;463(1):89-101. doi: 10.1016/j.abb.2007.03.006. Epub 2007 Apr 2. Arch Biochem Biophys. 2007. PMID: 17459328 Free PMC article.

10

Functional promiscuity correlates with conformational heterogeneity in A-class glutathione S-transferases.

Hou L, Honaker MT, Shireman LM, Balogh LM, Roberts AG, Ng KC, Nath A, Atkins WM. Hou L, et al. Among authors: atkins wm. J Biol Chem. 2007 Aug 10;282(32):23264-74. doi: 10.1074/jbc.M700868200. Epub 2007 Jun 8. J Biol Chem. 2007. PMID: 17561509 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

145 results

Search Page

Filters