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205 results

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Page 1
Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties.
Biava M, Porretta GC, Poce G, Battilocchio C, Alfonso S, Rovini M, Valenti S, Giorgi G, Calderone V, Martelli A, Testai L, Sautebin L, Rossi A, Papa G, Ghelardini C, Di Cesare Mannelli L, Giordani A, Anzellotti P, Bruno A, Patrignani P, Anzini M. Biava M, et al. Among authors: patrignani p. J Med Chem. 2011 Nov 24;54(22):7759-71. doi: 10.1021/jm200715n. Epub 2011 Oct 31. J Med Chem. 2011. PMID: 21992176
Human pharmacology of naproxen sodium.
Capone ML, Tacconelli S, Sciulli MG, Anzellotti P, Di Francesco L, Merciaro G, Di Gregorio P, Patrignani P. Capone ML, et al. Among authors: patrignani p. J Pharmacol Exp Ther. 2007 Aug;322(2):453-60. doi: 10.1124/jpet.107.122283. Epub 2007 May 1. J Pharmacol Exp Ther. 2007. PMID: 17473175 Clinical Trial.
Cyclooxygenase-2 inhibitors. 1,5-diarylpyrrol-3-acetic esters with enhanced inhibitory activity toward cyclooxygenase-2 and improved cyclooxygenase-2/cyclooxygenase-1 selectivity.
Biava M, Porretta GC, Poce G, Supino S, Forli S, Rovini M, Cappelli A, Manetti F, Botta M, Sautebin L, Rossi A, Pergola C, Ghelardini C, Vivoli E, Makovec F, Anzellotti P, Patrignani P, Anzini M. Biava M, et al. Among authors: patrignani p. J Med Chem. 2007 Nov 1;50(22):5403-11. doi: 10.1021/jm0707525. Epub 2007 Oct 4. J Med Chem. 2007. PMID: 17915854 Free article.
Synthesis, biological evaluation, and enzyme docking simulations of 1,5-diarylpyrrole-3-alkoxyethyl ethers as selective cyclooxygenase-2 inhibitors endowed with anti-inflammatory and antinociceptive activity.
Anzini M, Rovini M, Cappelli A, Vomero S, Manetti F, Botta M, Sautebin L, Rossi A, Pergola C, Ghelardini C, Norcini M, Giordani A, Makovec F, Anzellotti P, Patrignani P, Biava M. Anzini M, et al. Among authors: patrignani p. J Med Chem. 2008 Aug 14;51(15):4476-81. doi: 10.1021/jm800084s. Epub 2008 Jul 4. J Med Chem. 2008. PMID: 18598017
Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents.
Biava M, Porretta GC, Poce G, Supino S, Manetti F, Forli S, Botta M, Sautebin L, Rossi A, Pergola C, Ghelardini C, Norcini M, Makovec F, Giordani A, Anzellotti P, Cirilli R, Ferretti R, Gallinella B, La Torre F, Anzini M, Patrignani P. Biava M, et al. Among authors: patrignani p. Bioorg Med Chem. 2008 Sep 1;16(17):8072-81. doi: 10.1016/j.bmc.2008.07.058. Epub 2008 Jul 24. Bioorg Med Chem. 2008. PMID: 18752957
Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro.
Bruno A, Di Francesco L, Coletta I, Mangano G, Alisi MA, Polenzani L, Milanese C, Anzellotti P, Ricciotti E, Dovizio M, Di Francesco A, Tacconelli S, Capone ML, Patrignani P. Bruno A, et al. Among authors: patrignani p. Biochem Pharmacol. 2010 Apr 1;79(7):974-81. doi: 10.1016/j.bcp.2009.11.011. Epub 2009 Nov 27. Biochem Pharmacol. 2010. PMID: 19925781
Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation.
Biava M, Porretta GC, Poce G, Battilocchio C, Manetti F, Botta M, Forli S, Sautebin L, Rossi A, Pergola C, Ghelardini C, Galeotti N, Makovec F, Giordani A, Anzellotti P, Patrignani P, Anzini M. Biava M, et al. Among authors: patrignani p. J Med Chem. 2010 Jan 28;53(2):723-33. doi: 10.1021/jm901269y. J Med Chem. 2010. PMID: 19957931 Free article.
Enlarging the NSAIDs family: ether, ester and acid derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents.
Biava M, Porretta GC, Poce G, Battilocchio C, Botta M, Manetti F, Rovini M, Cappelli A, Sautebin L, Rossi A, Pergola C, Ghelardini C, Galeotti N, Makovec F, Giordani A, Anzellotti P, Tacconelli S, Patrignani P, Anzini M. Biava M, et al. Among authors: patrignani p. Curr Med Chem. 2011;18(10):1540-54. doi: 10.2174/092986711795328364. Curr Med Chem. 2011. PMID: 21428878 Free article. Review.
205 results