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Generation and structure-activity relationships of novel imidazo-thienopyridine based TLR7 agonists: application as payloads for immunostimulatory antibody drug-conjugates.
Brant MG, Garnett GAE, Guedia J, Lasalle M, Lawn S, Petersen ME, Duan R, Mendez-Campos J, Hirkala-Schaefer T, Winters GC, Barnscher SD. Brant MG, et al. Bioorg Med Chem Lett. 2023 Jul 15;91:129348. doi: 10.1016/j.bmcl.2023.129348. Epub 2023 May 20. Bioorg Med Chem Lett. 2023. PMID: 37217025
Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates.
Petersen ME, Brant MG, Lasalle M, Das S, Duan R, Wong J, Ding T, Wu KJ, Siddappa D, Fang C, Zhang W, Wu AML, Hirkala-Schaefer T, Garnett GAE, Fung V, Yang L, Hernandez Rojas A, Lawn SO, Barnscher SD, Rich JR, Colombo R. Petersen ME, et al. Among authors: brant mg. Mol Cancer Ther. 2024 May 2;23(5):606-618. doi: 10.1158/1535-7163.MCT-23-0822. Mol Cancer Ther. 2024. PMID: 38354417 Free PMC article.