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Page 1
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia.
Coulon S, Dussiot M, Grapton D, Maciel TT, Wang PH, Callens C, Tiwari MK, Agarwal S, Fricot A, Vandekerckhove J, Tamouza H, Zermati Y, Ribeil JA, Djedaini K, Oruc Z, Pascal V, Courtois G, Arnulf B, Alyanakian MA, Mayeux P, Leanderson T, Benhamou M, Cogné M, Monteiro RC, Hermine O, Moura IC. Coulon S, et al. Among authors: maciel tt. Nat Med. 2011 Oct 23;17(11):1456-65. doi: 10.1038/nm.2462. Nat Med. 2011. PMID: 22019886
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.
Green AS, Chapuis N, Maciel TT, Willems L, Lambert M, Arnoult C, Boyer O, Bardet V, Park S, Foretz M, Viollet B, Ifrah N, Dreyfus F, Hermine O, Moura IC, Lacombe C, Mayeux P, Bouscary D, Tamburini J. Green AS, et al. Among authors: maciel tt. Blood. 2010 Nov 18;116(20):4262-73. doi: 10.1182/blood-2010-02-269837. Epub 2010 Jul 28. Blood. 2010. PMID: 20668229 Free article.
The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.
Willems L, Chapuis N, Puissant A, Maciel TT, Green AS, Jacque N, Vignon C, Park S, Guichard S, Herault O, Fricot A, Hermine O, Moura IC, Auberger P, Ifrah N, Dreyfus F, Bonnet D, Lacombe C, Mayeux P, Bouscary D, Tamburini J. Willems L, et al. Among authors: maciel tt. Leukemia. 2012 Jun;26(6):1195-202. doi: 10.1038/leu.2011.339. Epub 2011 Dec 6. Leukemia. 2012. PMID: 22143671
Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.
Berthelot L, Papista C, Maciel TT, Biarnes-Pelicot M, Tissandie E, Wang PH, Tamouza H, Jamin A, Bex-Coudrat J, Gestin A, Boumediene A, Arcos-Fajardo M, England P, Pillebout E, Walker F, Daugas E, Vrtosvnik F, Flamant M, Benhamou M, Cogné M, Moura IC, Monteiro RC. Berthelot L, et al. Among authors: maciel tt. J Exp Med. 2012 Apr 9;209(4):793-806. doi: 10.1084/jem.20112005. Epub 2012 Mar 26. J Exp Med. 2012. PMID: 22451718 Free PMC article.
[Regulation of erythropoiesis mediated by immunoglobulin A1].
Coulon S, Dussiot M, Grapton D, Rossignol J, Maciel TT, Benhamou M, Monteiro RC, Hermine O, Moura IC. Coulon S, et al. Among authors: maciel tt. Med Sci (Paris). 2012 Aug-Sep;28(8-9):692-5. doi: 10.1051/medsci/2012288006. Epub 2012 Aug 22. Med Sci (Paris). 2012. PMID: 22920866 Free article. French. No abstract available.
Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.
Willems L, Jacque N, Jacquel A, Neveux N, Maciel TT, Lambert M, Schmitt A, Poulain L, Green AS, Uzunov M, Kosmider O, Radford-Weiss I, Moura IC, Auberger P, Ifrah N, Bardet V, Chapuis N, Lacombe C, Mayeux P, Tamburini J, Bouscary D. Willems L, et al. Among authors: maciel tt. Blood. 2013 Nov 14;122(20):3521-32. doi: 10.1182/blood-2013-03-493163. Epub 2013 Sep 6. Blood. 2013. PMID: 24014241 Free PMC article.
An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia.
Dussiot M, Maciel TT, Fricot A, Chartier C, Negre O, Veiga J, Grapton D, Paubelle E, Payen E, Beuzard Y, Leboulch P, Ribeil JA, Arlet JB, Coté F, Courtois G, Ginzburg YZ, Daniel TO, Chopra R, Sung V, Hermine O, Moura IC. Dussiot M, et al. Among authors: maciel tt. Nat Med. 2014 Apr;20(4):398-407. doi: 10.1038/nm.3468. Epub 2014 Mar 23. Nat Med. 2014. PMID: 24658077 Free PMC article.
HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia.
Arlet JB, Ribeil JA, Guillem F, Negre O, Hazoume A, Marcion G, Beuzard Y, Dussiot M, Moura IC, Demarest S, de Beauchêne IC, Belaid-Choucair Z, Sevin M, Maciel TT, Auclair C, Leboulch P, Chretien S, Tchertanov L, Baudin-Creuza V, Seigneuric R, Fontenay M, Garrido C, Hermine O, Courtois G. Arlet JB, et al. Among authors: maciel tt. Nature. 2014 Oct 9;514(7521):242-6. doi: 10.1038/nature13614. Epub 2014 Aug 24. Nature. 2014. PMID: 25156257
The role of mast cells in cancers.
Maciel TT, Moura IC, Hermine O. Maciel TT, et al. F1000Prime Rep. 2015 Jan 5;7:09. doi: 10.12703/P7-09. eCollection 2015. F1000Prime Rep. 2015. PMID: 25705392 Free PMC article. Review.
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Jacque N, Ronchetti AM, Larrue C, Meunier G, Birsen R, Willems L, Saland E, Decroocq J, Maciel TT, Lambert M, Poulain L, Hospital MA, Sujobert P, Joseph L, Chapuis N, Lacombe C, Moura IC, Demo S, Sarry JE, Recher C, Mayeux P, Tamburini J, Bouscary D. Jacque N, et al. Among authors: maciel tt. Blood. 2015 Sep 10;126(11):1346-56. doi: 10.1182/blood-2015-01-621870. Epub 2015 Jul 17. Blood. 2015. PMID: 26186940 Free PMC article.
52 results