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Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer.
Friedbichler K, Themanns M, Mueller KM, Schlederer M, Kornfeld JW, Terracciano LM, Kozlov AV, Haindl S, Kenner L, Kolbe T, Mueller M, Snibson KJ, Heim MH, Moriggl R. Friedbichler K, et al. Among authors: kornfeld jw. Hepatology. 2012 Mar;55(3):941-52. doi: 10.1002/hep.24765. Epub 2012 Jan 13. Hepatology. 2012. PMID: 22031092
The different functions of Stat5 and chromatin alteration through Stat5 proteins.
Kornfeld JW, Grebien F, Kerenyi MA, Friedbichler K, Kovacic B, Zankl B, Hoelbl A, Nivarti H, Beug H, Sexl V, Muller M, Kenner L, Mullner EW, Gouilleux F, Moriggl R. Kornfeld JW, et al. Front Biosci. 2008 May 1;13:6237-54. doi: 10.2741/3151. Front Biosci. 2008. PMID: 18508657 Free PMC article. Review.
Expression of activated STAT5 in neoplastic mast cells in systemic mastocytosis: subcellular distribution and role of the transforming oncoprotein KIT D816V.
Baumgartner C, Cerny-Reiterer S, Sonneck K, Mayerhofer M, Gleixner KV, Fritz R, Kerenyi M, Boudot C, Gouilleux F, Kornfeld JW, Sillaber C, Moriggl R, Valent P. Baumgartner C, et al. Among authors: kornfeld jw. Am J Pathol. 2009 Dec;175(6):2416-29. doi: 10.2353/ajpath.2009.080953. Epub 2009 Nov 5. Am J Pathol. 2009. PMID: 19893034 Free PMC article.
Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.
Blaas L, Kornfeld JW, Schramek D, Musteanu M, Zollner G, Gumhold J, van Zijl F, Schneller D, Esterbauer H, Egger G, Mair M, Kenner L, Mikulits W, Eferl R, Moriggl R, Penninger J, Trauner M, Casanova E. Blaas L, et al. Among authors: kornfeld jw. Hepatology. 2010 Apr;51(4):1319-26. doi: 10.1002/hep.23469. Hepatology. 2010. PMID: 20162728 Free PMC article.
Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis.
Mair M, Zollner G, Schneller D, Musteanu M, Fickert P, Gumhold J, Schuster C, Fuchsbichler A, Bilban M, Tauber S, Esterbauer H, Kenner L, Poli V, Blaas L, Kornfeld JW, Casanova E, Mikulits W, Trauner M, Eferl R. Mair M, et al. Among authors: kornfeld jw. Gastroenterology. 2010 Jun;138(7):2499-508. doi: 10.1053/j.gastro.2010.02.049. Epub 2010 Feb 26. Gastroenterology. 2010. PMID: 20193684
Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.
Mueller KM, Kornfeld JW, Friedbichler K, Blaas L, Egger G, Esterbauer H, Hasselblatt P, Schlederer M, Haindl S, Wagner KU, Engblom D, Haemmerle G, Kratky D, Sexl V, Kenner L, Kozlov AV, Terracciano L, Zechner R, Schuetz G, Casanova E, Pospisilik JA, Heim MH, Moriggl R. Mueller KM, et al. Among authors: kornfeld jw. Hepatology. 2011 Oct;54(4):1398-409. doi: 10.1002/hep.24509. Hepatology. 2011. PMID: 21725989 Free PMC article.
Variants in STAT5B associate with serum TC and LDL-C levels.
Kornfeld JW, Isaacs A, Vitart V, Pospisilik JA, Meitinger T, Gyllensten U, Wilson JF, Rudan I, Campbell H, Penninger JM, Sexl V, Moriggl R, van Duijn C, Pramstaller PP, Hicks AA. Kornfeld JW, et al. J Clin Endocrinol Metab. 2011 Sep;96(9):E1496-501. doi: 10.1210/jc.2011-0322. Epub 2011 Jul 13. J Clin Endocrinol Metab. 2011. PMID: 21752895
32 results