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DNA methylation aberrations rather than polymorphisms of FZD3 gene increase the risk of spina bifida in a high-risk region for neural tube defects.
Shangguan S, Wang L, Chang S, Lu X, Wang Z, Wu L, Wang J, Wang X, Guan Z, Bao Y, Zhao H, Zou J, Niu B, Zhang T. Shangguan S, et al. Among authors: lu x. Birth Defects Res A Clin Mol Teratol. 2015 Jan;103(1):37-44. doi: 10.1002/bdra.23285. Epub 2014 Aug 18. Birth Defects Res A Clin Mol Teratol. 2015. PMID: 25131656
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