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Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis.
Molenaar JJ, Koster J, Ebus ME, van Sluis P, Westerhout EM, de Preter K, Gisselsson D, Øra I, Speleman F, Caron HN, Versteeg R. Molenaar JJ, et al. Among authors: speleman f. Genes Chromosomes Cancer. 2012 Jan;51(1):10-9. doi: 10.1002/gcc.20926. Epub 2011 Oct 27. Genes Chromosomes Cancer. 2012. PMID: 22034077
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients.
Van Roy N, Vandesompele J, Berx G, Staes K, Van Gele M, De Smet E, De Paepe A, Laureys G, van der Drift P, Versteeg R, Van Roy F, Speleman F. Van Roy N, et al. Among authors: speleman f. Genes Chromosomes Cancer. 2002 Oct;35(2):113-20. doi: 10.1002/gcc.10034. Genes Chromosomes Cancer. 2002. PMID: 12203774
No evidence for involvement of SDHD in neuroblastoma pathogenesis.
De Preter K, Vandesompele J, Hoebeeck J, Vandenbroecke C, Smet J, Nuyts A, Laureys G, Combaret V, Van Roy N, Roels F, Van Coster R, Praet M, De Paepe A, Speleman F. De Preter K, et al. Among authors: speleman f. BMC Cancer. 2004 Aug 24;4:55. doi: 10.1186/1471-2407-4-55. BMC Cancer. 2004. PMID: 15331017 Free PMC article.
ArrayCGH-based classification of neuroblastoma into genomic subgroups.
Michels E, Vandesompele J, De Preter K, Hoebeeck J, Vermeulen J, Schramm A, Molenaar JJ, Menten B, Marques B, Stallings RL, Combaret V, Devalck C, De Paepe A, Versteeg R, Eggert A, Laureys G, Van Roy N, Speleman F. Michels E, et al. Among authors: speleman f. Genes Chromosomes Cancer. 2007 Dec;46(12):1098-108. doi: 10.1002/gcc.20496. Genes Chromosomes Cancer. 2007. PMID: 17823929
412 results