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The biologically crucial C terminus of cholecystokinin and the non-peptide agonist SR-146,131 share a common binding site in the human CCK1 receptor. Evidence for a crucial role of Met-121 in the activation process.
Escrieut C, Gigoux V, Archer E, Verrier S, Maigret B, Behrendt R, Moroder L, Bignon E, Silvente-Poirot S, Pradayrol L, Fourmy D. Escrieut C, et al. Among authors: gigoux v. J Biol Chem. 2002 Mar 1;277(9):7546-55. doi: 10.1074/jbc.M108563200. Epub 2001 Nov 27. J Biol Chem. 2002. PMID: 11724786 Free article.
Identification of putative amino acids of the CCK1R binding site was achieved by dynamics-based docking of the ligand CCK in a refined three-dimensional model of the CCK1R using, as constraints, previous results that identified contact points between residues of CCK and CCK1R (Ke …
Identification of putative amino acids of the CCK1R binding site was achieved by dynamics-based docking of the ligand CCK in a refined three …
Reg genes are CCK2 receptor targets in ElasCCK2 mice pancreas.
Gigoux V, Clerc P, Sanchez D, Coll MG, Corominola H, Leung-Theung-Long S, Pénicaud L, Gomis R, Seva C, Fourmy D, Dufresne M. Gigoux V, et al. Regul Pept. 2008 Feb 7;146(1-3):88-98. doi: 10.1016/j.regpep.2007.08.020. Epub 2007 Aug 31. Regul Pept. 2008. PMID: 17888528
Id3 modulates cellular localization of bHLH Ptf1-p48 protein.
Dufresne M, Clerc P, Dieng M, Edir A, Couvelard A, Delisle MB, Fourmy D, Gigoux V. Dufresne M, et al. Among authors: gigoux v. Int J Cancer. 2011 Jul 15;129(2):295-306. doi: 10.1002/ijc.25668. Epub 2010 Nov 3. Int J Cancer. 2011. PMID: 20830706
42 results