Ruchala P - Search Results

1

Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload.

Preza GC, Ruchala P, Pinon R, Ramos E, Qiao B, Peralta MA, Sharma S, Waring A, Ganz T, Nemeth E. Preza GC, et al. Among authors: ruchala p. J Clin Invest. 2011 Dec;121(12):4880-8. doi: 10.1172/JCI57693. J Clin Invest. 2011. PMID: 22045566 Free PMC article.

2

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis.

Ramos E, Ruchala P, Goodnough JB, Kautz L, Preza GC, Nemeth E, Ganz T. Ramos E, et al. Among authors: ruchala p. Blood. 2012 Nov 1;120(18):3829-36. doi: 10.1182/blood-2012-07-440743. Epub 2012 Sep 18. Blood. 2012. PMID: 22990014 Free PMC article.

3

The pathophysiology and pharmacology of hepcidin.

Ruchala P, Nemeth E. Ruchala P, et al. Trends Pharmacol Sci. 2014 Mar;35(3):155-61. doi: 10.1016/j.tips.2014.01.004. Epub 2014 Feb 17. Trends Pharmacol Sci. 2014. PMID: 24552640 Free PMC article. Review.

4

Thiol-derivatized minihepcidins retain biological activity.

Fung E, Chua K, Ganz T, Nemeth E, Ruchala P. Fung E, et al. Among authors: ruchala p. Bioorg Med Chem Lett. 2015 Feb 15;25(4):763-6. doi: 10.1016/j.bmcl.2014.12.094. Epub 2015 Jan 6. Bioorg Med Chem Lett. 2015. PMID: 25599838 Free PMC article.

5

Small cyclic agonists of iron regulatory hormone hepcidin.

Chua K, Fung E, Micewicz ED, Ganz T, Nemeth E, Ruchala P. Chua K, et al. Among authors: ruchala p. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4961-4969. doi: 10.1016/j.bmcl.2015.03.012. Epub 2015 Mar 12. Bioorg Med Chem Lett. 2015. PMID: 25813158 Free PMC article.

6

Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus.

Arezes J, Jung G, Gabayan V, Valore E, Ruchala P, Gulig PA, Ganz T, Nemeth E, Bulut Y. Arezes J, et al. Among authors: ruchala p. Cell Host Microbe. 2015 Jan 14;17(1):47-57. doi: 10.1016/j.chom.2014.12.001. Cell Host Microbe. 2015. PMID: 25590758 Free PMC article.

7

Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron.

Stefanova D, Raychev A, Arezes J, Ruchala P, Gabayan V, Skurnik M, Dillon BJ, Horwitz MA, Ganz T, Bulut Y, Nemeth E. Stefanova D, et al. Among authors: ruchala p. Blood. 2017 Jul 20;130(3):245-257. doi: 10.1182/blood-2017-03-772715. Epub 2017 May 2. Blood. 2017. PMID: 28465342 Free PMC article.

8

Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients.

Stefanova D, Raychev A, Deville J, Humphries R, Campeau S, Ruchala P, Nemeth E, Ganz T, Bulut Y. Stefanova D, et al. Among authors: ruchala p. Infect Immun. 2018 Jun 21;86(7):e00253-18. doi: 10.1128/IAI.00253-18. Print 2018 Jul. Infect Immun. 2018. PMID: 29735522 Free PMC article.

9

Maternal hepcidin determines embryo iron homeostasis in mice.

Sangkhae V, Fisher AL, Chua KJ, Ruchala P, Ganz T, Nemeth E. Sangkhae V, et al. Among authors: ruchala p. Blood. 2020 Nov 5;136(19):2206-2216. doi: 10.1182/blood.2020005745. Blood. 2020. PMID: 32584957 Free PMC article.

10

Oxpholipin 11D: an anti-inflammatory peptide that binds cholesterol and oxidized phospholipids.

Ruchala P, Navab M, Jung CL, Hama-Levy S, Micewicz ED, Luong H, Reyles JE, Sharma S, Waring AJ, Fogelman AM, Lehrer RI. Ruchala P, et al. PLoS One. 2010 Apr 14;5(4):e10181. doi: 10.1371/journal.pone.0010181. PLoS One. 2010. PMID: 20418958 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

68 results

Search Page

Filters