Waldmann H - Search Results

1

Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases.

Bürger M, Zimmermann TJ, Kondoh Y, Stege P, Watanabe N, Osada H, Waldmann H, Vetter IR. Bürger M, et al. Among authors: waldmann h. J Lipid Res. 2012 Jan;53(1):43-50. doi: 10.1194/jlr.M019851. Epub 2011 Nov 3. J Lipid Res. 2012. PMID: 22052940 Free PMC article.

2

From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries.

Breinbauer R, Vetter IR, Waldmann H. Breinbauer R, et al. Among authors: waldmann h. Angew Chem Int Ed Engl. 2002 Aug 16;41(16):2879-90. doi: 10.1002/1521-3773(20020816)41:16<2878::AID-ANIE2878>3.0.CO;2-B. Angew Chem Int Ed Engl. 2002. PMID: 12203413 Review.

3

From protein domains to drug candidates--natural products as guiding principles in compound library design and synthesis.

Breinbauer R, Vetter IR, Waldmann H. Breinbauer R, et al. Among authors: waldmann h. Ernst Schering Res Found Workshop. 2003;(42):167-88. doi: 10.1007/978-3-662-05314-0_11. Ernst Schering Res Found Workshop. 2003. PMID: 12664541 No abstract available.

4

Principles, implementation, and application of biology-oriented synthesis (BIOS).

Wilk W, Zimmermann TJ, Kaiser M, Waldmann H. Wilk W, et al. Among authors: waldmann h. Biol Chem. 2010 May;391(5):491-7. doi: 10.1515/BC.2010.013. Biol Chem. 2010. PMID: 20030592 Free article. Review.

5

Design and evaluation of fragment-like estrogen receptor tetrahydroisoquinoline ligands from a scaffold-detection approach.

Möcklinghoff S, van Otterlo WA, Rose R, Fuchs S, Zimmermann TJ, Dominguez Seoane M, Waldmann H, Ottmann C, Brunsveld L. Möcklinghoff S, et al. Among authors: waldmann h. J Med Chem. 2011 Apr 14;54(7):2005-11. doi: 10.1021/jm1011116. Epub 2011 Mar 7. J Med Chem. 2011. PMID: 21381753

6

Development of highly potent inhibitors of the Ras-targeting human acyl protein thioesterases based on substrate similarity design.

Hedberg C, Dekker FJ, Rusch M, Renner S, Wetzel S, Vartak N, Gerding-Reimers C, Bon RS, Bastiaens PI, Waldmann H. Hedberg C, et al. Among authors: waldmann h. Angew Chem Int Ed Engl. 2011 Oct 10;50(42):9832-7. doi: 10.1002/anie.201102965. Epub 2011 Sep 9. Angew Chem Int Ed Engl. 2011. PMID: 21905185

7

Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras-signaling modulators palmostatin B and M.

Rusch M, Zimmermann TJ, Bürger M, Dekker FJ, Görmer K, Triola G, Brockmeyer A, Janning P, Böttcher T, Sieber SA, Vetter IR, Hedberg C, Waldmann H. Rusch M, et al. Among authors: waldmann h. Angew Chem Int Ed Engl. 2011 Oct 10;50(42):9838-42. doi: 10.1002/anie.201102967. Epub 2011 Sep 9. Angew Chem Int Ed Engl. 2011. PMID: 21905186

8

Revealing conformational substates of lipidated N-Ras protein by pressure modulation.

Kapoor S, Triola G, Vetter IR, Erlkamp M, Waldmann H, Winter R. Kapoor S, et al. Among authors: waldmann h. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):460-5. doi: 10.1073/pnas.1110553109. Epub 2011 Dec 27. Proc Natl Acad Sci U S A. 2012. PMID: 22203965 Free PMC article.

9

Chemical-biological exploration of the limits of the Ras de- and repalmitoylating machinery.

Görmer K, Bürger M, Kruijtzer JA, Vetter I, Vartak N, Brunsveld L, Bastiaens PI, Liskamp RM, Triola G, Waldmann H. Görmer K, et al. Among authors: waldmann h. Chembiochem. 2012 May 7;13(7):1017-23. doi: 10.1002/cbic.201200078. Epub 2012 Apr 5. Chembiochem. 2012. PMID: 22488913

10

Boron-based inhibitors of acyl protein thioesterases 1 and 2.

Zimmermann TJ, Bürger M, Tashiro E, Kondoh Y, Martinez NE, Görmer K, Rosin-Steiner S, Shimizu T, Ozaki S, Mikoshiba K, Watanabe N, Hall D, Vetter IR, Osada H, Hedberg C, Waldmann H. Zimmermann TJ, et al. Among authors: waldmann h. Chembiochem. 2013 Jan 2;14(1):115-22. doi: 10.1002/cbic.201200571. Epub 2012 Dec 13. Chembiochem. 2013. PMID: 23239555

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