Tonelli R - Search Results

1

Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy.

Tonelli R, McIntyre A, Camerin C, Walters ZS, Di Leo K, Selfe J, Purgato S, Missiaglia E, Tortori A, Renshaw J, Astolfi A, Taylor KR, Serravalle S, Bishop R, Nanni C, Valentijn LJ, Faccini A, Leuschner I, Formica S, Reis-Filho JS, Ambrosini V, Thway K, Franzoni M, Summersgill B, Marchelli R, Hrelia P, Cantelli-Forti G, Fanti S, Corradini R, Pession A, Shipley J. Tonelli R, et al. Clin Cancer Res. 2012 Feb 1;18(3):796-807. doi: 10.1158/1078-0432.CCR-11-1981. Epub 2011 Nov 7. Clin Cancer Res. 2012. PMID: 22065083

2

Targeted inhibition of NMYC by peptide nucleic acid in N-myc amplified human neuroblastoma cells: cell-cycle inhibition with induction of neuronal cell differentiation and apoptosis.

Pession A, Tonelli R, Fronza R, Sciamanna E, Corradini R, Sforza S, Tedeschi T, Marchelli R, Montanaro L, Camerin C, Franzoni M, Paolucci G. Pession A, et al. Among authors: tonelli r. Int J Oncol. 2004 Feb;24(2):265-72. Int J Oncol. 2004. PMID: 14719101

3

Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis.

Tonelli R, Purgato S, Camerin C, Fronza R, Bologna F, Alboresi S, Franzoni M, Corradini R, Sforza S, Faccini A, Shohet JM, Marchelli R, Pession A. Tonelli R, et al. Mol Cancer Ther. 2005 May;4(5):779-86. doi: 10.1158/1535-7163.MCT-04-0213. Mol Cancer Ther. 2005. PMID: 15897242

4

The MYCN oncogene as a specific and selective drug target for peripheral and central nervous system tumors.

Pession A, Tonelli R. Pession A, et al. Among authors: tonelli r. Curr Cancer Drug Targets. 2005 Jun;5(4):273-83. doi: 10.2174/1568009054064606. Curr Cancer Drug Targets. 2005. PMID: 15975048 Review.

5

Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice.

Bergantin E, Quarta C, Nanni C, Fanti S, Pession A, Cantelli-Forti G, Tonelli R, Hrelia P. Bergantin E, et al. Among authors: tonelli r. Cancer Biol Ther. 2014 Sep;15(9):1219-25. doi: 10.4161/cbt.29684. Epub 2014 Jun 27. Cancer Biol Ther. 2014. PMID: 24971463 Free PMC article.

6

A Novel MYCN-Specific Antigene Oligonucleotide Deregulates Mitochondria and Inhibits Tumor Growth in MYCN-Amplified Neuroblastoma.

Montemurro L, Raieli S, Angelucci S, Bartolucci D, Amadesi C, Lampis S, Scardovi AL, Venturelli L, Nieddu G, Cerisoli L, Fischer M, Teti G, Falconi M, Pession A, Hrelia P, Tonelli R. Montemurro L, et al. Among authors: tonelli r. Cancer Res. 2019 Dec 15;79(24):6166-6177. doi: 10.1158/0008-5472.CAN-19-0008. Epub 2019 Oct 15. Cancer Res. 2019. PMID: 31615807

7

The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma.

Lampis S, Raieli S, Montemurro L, Bartolucci D, Amadesi C, Bortolotti S, Angelucci S, Scardovi AL, Nieddu G, Cerisoli L, Paganelli F, Valente S, Fischer M, Martelli AM, Pasquinelli G, Pession A, Hrelia P, Tonelli R. Lampis S, et al. Among authors: tonelli r. J Exp Clin Cancer Res. 2022 Apr 30;41(1):160. doi: 10.1186/s13046-022-02367-5. J Exp Clin Cancer Res. 2022. PMID: 35490242 Free PMC article.

8

Down-regulation of MLL-AF9, MLL and MYC expression is not obligatory for monocyte-macrophage maturation in AML-M5 cell lines carrying t(9;11)(p22;q23).

Martino V, Tonelli R, Montemurro L, Franzoni M, Marino F, Fazzina R, Pession A. Martino V, et al. Among authors: tonelli r. Oncol Rep. 2006 Jan;15(1):207-11. Oncol Rep. 2006. PMID: 16328057

9

Circular dichroism study of DNA binding by a potential anticancer peptide nucleic acid targeted against the MYCN oncogene.

Faccini A, Tortori A, Tedeschi T, Sforza S, Tonelli R, Pession A, Corradini R, Marchelli R. Faccini A, et al. Among authors: tonelli r. Chirality. 2008 Mar;20(3-4):494-500. doi: 10.1002/chir.20489. Chirality. 2008. PMID: 17963203

10

Molecular imaging of neuroblastoma progression in TH-MYCN transgenic mice.

Quarta C, Cantelli E, Nanni C, Ambrosini V, D'ambrosio D, Di Leo K, Angelucci S, Zagni F, Lodi F, Marengo M, Weiss WA, Pession A, Tonelli R, Fanti S. Quarta C, et al. Among authors: tonelli r. Mol Imaging Biol. 2013 Apr;15(2):194-202. doi: 10.1007/s11307-012-0576-9. Mol Imaging Biol. 2013. PMID: 22777578 Free PMC article.

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