Lavie A - Search Results

1

Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe.

Campbell DO, Yaghoubi SS, Su Y, Lee JT, Auerbach MS, Herschman H, Satyamurthy N, Czernin J, Lavie A, Radu CG. Campbell DO, et al. Among authors: lavie a. J Biol Chem. 2012 Jan 2;287(1):446-454. doi: 10.1074/jbc.M111.314666. Epub 2011 Nov 9. J Biol Chem. 2012. PMID: 22074768 Free PMC article. Clinical Trial.

2

Modifying human thymidylate kinase to potentiate azidothymidine activation.

Brundiers R, Lavie A, Veit T, Reinstein J, Schlichting I, Ostermann N, Goody RS, Konrad M. Brundiers R, et al. Among authors: lavie a. J Biol Chem. 1999 Dec 10;274(50):35289-92. doi: 10.1074/jbc.274.50.35289. J Biol Chem. 1999. PMID: 10585390 Free article.

3

Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains.

Li Y, Spangenberg O, Paarmann I, Konrad M, Lavie A. Li Y, et al. Among authors: lavie a. J Biol Chem. 2002 Feb 8;277(6):4159-65. doi: 10.1074/jbc.M110792200. Epub 2001 Nov 29. J Biol Chem. 2002. PMID: 11729206 Free article.

4

Structural characterization of the closed conformation of mouse guanylate kinase.

Sekulic N, Shuvalova L, Spangenberg O, Konrad M, Lavie A. Sekulic N, et al. Among authors: lavie a. J Biol Chem. 2002 Aug 16;277(33):30236-43. doi: 10.1074/jbc.M204668200. Epub 2002 May 29. J Biol Chem. 2002. PMID: 12036965 Free article.

5

Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase.

Lavie A, Konrad M. Lavie A, et al. Mini Rev Med Chem. 2004 May;4(4):351-9. doi: 10.2174/1389557043403981. Mini Rev Med Chem. 2004. PMID: 15134538 Review.

6

Substrate-induced conformational changes in human UMP/CMP kinase.

Segura-Peña D, Sekulic N, Ort S, Konrad M, Lavie A. Segura-Peña D, et al. Among authors: lavie a. J Biol Chem. 2004 Aug 6;279(32):33882-9. doi: 10.1074/jbc.M401989200. Epub 2004 May 26. J Biol Chem. 2004. PMID: 15163660 Free article.

7

Specific amino acids in the first fibronectin type III repeat of the neural cell adhesion molecule play a role in its recognition and polysialylation by the polysialyltransferase ST8Sia IV/PST.

Mendiratta SS, Sekulic N, Lavie A, Colley KJ. Mendiratta SS, et al. Among authors: lavie a. J Biol Chem. 2005 Sep 16;280(37):32340-8. doi: 10.1074/jbc.M506217200. Epub 2005 Jul 18. J Biol Chem. 2005. PMID: 16027151 Free article.

8

A novel alpha-helix in the first fibronectin type III repeat of the neural cell adhesion molecule is critical for N-glycan polysialylation.

Mendiratta SS, Sekulic N, Hernandez-Guzman FG, Close BE, Lavie A, Colley KJ. Mendiratta SS, et al. Among authors: lavie a. J Biol Chem. 2006 Nov 24;281(47):36052-9. doi: 10.1074/jbc.M608073200. Epub 2006 Sep 26. J Biol Chem. 2006. PMID: 17003032 Free article.

9

Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L- and D-nucleosides.

Sabini E, Hazra S, Konrad M, Lavie A. Sabini E, et al. Among authors: lavie a. J Med Chem. 2007 Jun 28;50(13):3004-14. doi: 10.1021/jm0700215. Epub 2007 May 27. J Med Chem. 2007. PMID: 17530837 Free PMC article.

10

Structural mechanism for substrate inhibition of the adenosine 5'-phosphosulfate kinase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 and its ramifications for enzyme regulation.

Sekulic N, Konrad M, Lavie A. Sekulic N, et al. Among authors: lavie a. J Biol Chem. 2007 Jul 27;282(30):22112-21. doi: 10.1074/jbc.M701713200. Epub 2007 May 31. J Biol Chem. 2007. PMID: 17540769 Free article.

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