Sinz MW - Search Results

1

Phenacetin pharmacokinetics in CYP1A2-deficient beagle dogs.

Whiterock VJ, Morgan DG, Lentz KA, Orcutt TL, Sinz MW. Whiterock VJ, et al. Among authors: sinz mw. Drug Metab Dispos. 2012 Feb;40(2):228-31. doi: 10.1124/dmd.111.041848. Epub 2011 Nov 10. Drug Metab Dispos. 2012. PMID: 22074769

2

Frequency of CYP1A2 polymorphism in beagle dogs.

Whiterock VJ, Delmonte TA, Hui LE, Orcutt TL, Sinz MW. Whiterock VJ, et al. Among authors: sinz mw. Drug Metab Lett. 2007 Apr;1(2):163-5. doi: 10.2174/187231207780363688. Drug Metab Lett. 2007. PMID: 19356037

3

Quantitative relationship between rifampicin exposure and induction of Cyp3a11 in SXR humanized mice: extrapolation to human CYP3A4 induction potential.

Kim S, Pray D, Zheng M, Morgan DG, Pizzano JG, Zoeckler ME, Chimalakonda A, Sinz MW. Kim S, et al. Among authors: sinz mw. Drug Metab Lett. 2008 Aug;2(3):169-75. doi: 10.2174/187231208785425809. Drug Metab Lett. 2008. PMID: 19356089

4

Evaluation of cynomolgus monkey pregnane X receptor, primary hepatocyte, and in vivo pharmacokinetic changes in predicting human CYP3A4 induction.

Kim S, Dinchuk JE, Anthony MN, Orcutt T, Zoeckler ME, Sauer MB, Mosure KW, Vuppugalla R, Grace JE Jr, Simmermacher J, Dulac HA, Pizzano J, Sinz M. Kim S, et al. Drug Metab Dispos. 2010 Jan;38(1):16-24. doi: 10.1124/dmd.109.029637. Drug Metab Dispos. 2010. PMID: 19833845

5

Pharmacokinetic-pharmacodynamic modeling of rifampicin-mediated Cyp3a11 induction in steroid and xenobiotic X receptor humanized mice.

Raybon JJ, Pray D, Morgan DG, Zoeckler M, Zheng M, Sinz M, Kim S. Raybon JJ, et al. J Pharmacol Exp Ther. 2011 Apr;337(1):75-82. doi: 10.1124/jpet.110.176677. Epub 2010 Dec 27. J Pharmacol Exp Ther. 2011. PMID: 21205914

6

Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition.

Gu X, Wang L, Gan J, Fancher RM, Tian Y, Hong Y, Lai Y, Sinz M, Shen H. Gu X, et al. Drug Metab Dispos. 2020 Aug;48(8):724-734. doi: 10.1124/dmd.120.090670. Epub 2020 Jun 1. Drug Metab Dispos. 2020. PMID: 32482623

7

Distribution of tacrine and metabolites in rat brain and plasma after single- and multiple-dose regimens. Evidence for accumulation of tacrine in brain tissue.

McNally WP, Pool WF, Sinz MW, Dehart P, Ortwine DF, Huang CC, Chang T, Woolf TF. McNally WP, et al. Among authors: sinz mw. Drug Metab Dispos. 1996 Jun;24(6):628-33. Drug Metab Dispos. 1996. PMID: 8781777

8

Expression and characterization of cynomolgus monkey cytochrome CYP3A4 in a novel human embryonic kidney cell-based mammalian system.

Selvakumar S, Bhutani P, Ghosh K, Krishnamurthy P, Kallipatti S, Selvam S, Ramarao M, Mandlekar S, Sinz MW, Rodrigues AD, Subramanian M. Selvakumar S, et al. Among authors: sinz mw. Drug Metab Dispos. 2014 Mar;42(3):369-76. doi: 10.1124/dmd.113.055491. Epub 2013 Dec 13. Drug Metab Dispos. 2014. PMID: 24335510

9

Detection of Weak Organic Anion-Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans.

Zhang Y, Holenarsipur VK, Kandoussi H, Zeng J, Mariappan TT, Sinz M, Shen H. Zhang Y, et al. Drug Metab Dispos. 2020 Oct;48(10):841-848. doi: 10.1124/dmd.120.000076. Epub 2020 Jul 28. Drug Metab Dispos. 2020. PMID: 32723847

10

Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A.

Panfen E, Chen W, Zhang Y, Sinz M, Marathe P, Gan J, Shen H. Panfen E, et al. Drug Metab Dispos. 2019 Nov;47(11):1352-1360. doi: 10.1124/dmd.119.087197. Epub 2019 Aug 19. Drug Metab Dispos. 2019. PMID: 31427432

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