Zhong W - Search Results

1

An adaptive mutation in NS2 is essential for efficient production of infectious 1b/2a chimeric hepatitis C virus in cell culture.

Chan K, Cheng G, Beran RK, Yang H, Appleby TC, Pokrovskii MV, Mo H, Zhong W, Delaney WE 4th. Chan K, et al. Among authors: zhong w. Virology. 2012 Jan 20;422(2):224-34. doi: 10.1016/j.virol.2011.10.022. Epub 2011 Nov 17. Virology. 2012. PMID: 22099378 Free article.

2

Novel mutations in a tissue culture-adapted hepatitis C virus strain improve infectious-virus stability and markedly enhance infection kinetics.

Pokrovskii MV, Bush CO, Beran RK, Robinson MF, Cheng G, Tirunagari N, Fenaux M, Greenstein AE, Zhong W, Delaney WE 4th, Paulson MS. Pokrovskii MV, et al. Among authors: zhong w. J Virol. 2011 Apr;85(8):3978-85. doi: 10.1128/JVI.01760-10. Epub 2011 Feb 2. J Virol. 2011. PMID: 21289124 Free PMC article.

3

Selection of clinically relevant protease inhibitor-resistant viruses using the genotype 2a hepatitis C virus infection system.

Cheng G, Chan K, Yang H, Corsa A, Pokrovskii M, Paulson M, Bahador G, Zhong W, Delaney W 4th. Cheng G, et al. Among authors: zhong w. Antimicrob Agents Chemother. 2011 May;55(5):2197-205. doi: 10.1128/AAC.01382-10. Epub 2011 Feb 28. Antimicrob Agents Chemother. 2011. PMID: 21357305 Free PMC article.

4

A small-molecule inhibitor of hepatitis C virus infectivity.

Bush CO, Pokrovskii MV, Saito R, Morganelli P, Canales E, Clarke MO, Lazerwith SE, Golde J, Reid BG, Babaoglu K, Pagratis N, Zhong W, Delaney WE 4th, Paulson MS, Beran RK. Bush CO, et al. Among authors: zhong w. Antimicrob Agents Chemother. 2014;58(1):386-96. doi: 10.1128/AAC.02083-13. Epub 2013 Oct 28. Antimicrob Agents Chemother. 2014. PMID: 24165192 Free PMC article.

5

Comparison of HCV NS3 protease and NS5B polymerase inhibitor activity in 1a, 1b and 2a replicons and 2a infectious virus.

Paulson MS, Yang H, Shih IH, Feng JY, Mabery EM, Robinson MF, Zhong W, Delaney WE 4th. Paulson MS, et al. Among authors: zhong w. Antiviral Res. 2009 Aug;83(2):135-42. doi: 10.1016/j.antiviral.2009.04.003. Epub 2009 Apr 14. Antiviral Res. 2009. PMID: 19457562

6

Cellular growth kinetics distinguish a cyclophilin inhibitor from an HSP90 inhibitor as a selective inhibitor of hepatitis C virus.

Beran RK, Sharma R, Corsa AC, Tian Y, Golde J, Lundgaard G, Delaney WE 4th, Zhong W, Greenstein AE. Beran RK, et al. Among authors: zhong w. PLoS One. 2012;7(2):e30286. doi: 10.1371/journal.pone.0030286. Epub 2012 Feb 8. PLoS One. 2012. PMID: 22347373 Free PMC article.

7

Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer.

Appleby TC, Luecke H, Shim JH, Wu JZ, Cheney IW, Zhong W, Vogeley L, Hong Z, Yao N. Appleby TC, et al. Among authors: zhong w. J Virol. 2005 Jan;79(1):277-88. doi: 10.1128/JVI.79.1.277-288.2005. J Virol. 2005. PMID: 15596823 Free PMC article.

8

Mechanistic characterization of GS-9190 (Tegobuvir), a novel nonnucleoside inhibitor of hepatitis C virus NS5B polymerase.

Shih IH, Vliegen I, Peng B, Yang H, Hebner C, Paeshuyse J, Pürstinger G, Fenaux M, Tian Y, Mabery E, Qi X, Bahador G, Paulson M, Lehman LS, Bondy S, Tse W, Reiser H, Lee WA, Schmitz U, Neyts J, Zhong W. Shih IH, et al. Among authors: zhong w. Antimicrob Agents Chemother. 2011 Sep;55(9):4196-203. doi: 10.1128/AAC.00307-11. Epub 2011 Jul 11. Antimicrob Agents Chemother. 2011. PMID: 21746939 Free PMC article.

9

Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug.

Feng JY, Cheng G, Perry J, Barauskas O, Xu Y, Fenaux M, Eng S, Tirunagari N, Peng B, Yu M, Tian Y, Lee YJ, Stepan G, Lagpacan LL, Jin D, Hung M, Ku KS, Han B, Kitrinos K, Perron M, Birkus G, Wong KA, Zhong W, Kim CU, Carey A, Cho A, Ray AS. Feng JY, et al. Among authors: zhong w. Antimicrob Agents Chemother. 2014;58(4):1930-42. doi: 10.1128/AAC.02351-13. Epub 2014 Jan 13. Antimicrob Agents Chemother. 2014. PMID: 24419349 Free PMC article.

10

Hepatitis C virus therapies: current treatments, targets and future perspectives.

Walker MP, Appleby TC, Zhong W, Lau JY, Hong Z. Walker MP, et al. Among authors: zhong w. Antivir Chem Chemother. 2003 Jan;14(1):1-21. doi: 10.1177/095632020301400101. Antivir Chem Chemother. 2003. PMID: 12790512 Free article. Review.

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