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Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death.
Rogers HA, Kilday JP, Mayne C, Ward J, Adamowicz-Brice M, Schwalbe EC, Clifford SC, Coyle B, Grundy RG. Rogers HA, et al. Among authors: clifford sc. Acta Neuropathol. 2012 May;123(5):711-25. doi: 10.1007/s00401-011-0904-1. Epub 2011 Nov 23. Acta Neuropathol. 2012. PMID: 22109108 Free PMC article.
Rapid diagnosis of medulloblastoma molecular subgroups.
Schwalbe EC, Lindsey JC, Straughton D, Hogg TL, Cole M, Megahed H, Ryan SL, Lusher ME, Taylor MD, Gilbertson RJ, Ellison DW, Bailey S, Clifford SC. Schwalbe EC, et al. Among authors: clifford sc. Clin Cancer Res. 2011 Apr 1;17(7):1883-94. doi: 10.1158/1078-0432.CCR-10-2210. Epub 2011 Feb 16. Clin Cancer Res. 2011. PMID: 21325292 Free PMC article.
TP53 mutations in favorable-risk Wnt/Wingless-subtype medulloblastomas.
Lindsey JC, Hill RM, Megahed H, Lusher ME, Schwalbe EC, Cole M, Hogg TL, Gilbertson RJ, Ellison DW, Bailey S, Clifford SC. Lindsey JC, et al. Among authors: clifford sc. J Clin Oncol. 2011 Apr 20;29(12):e344-6; author reply e347-8. doi: 10.1200/JCO.2010.33.8590. Epub 2011 Feb 28. J Clin Oncol. 2011. PMID: 21357788 No abstract available.
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct.
Northcott PA, Hielscher T, Dubuc A, Mack S, Shih D, Remke M, Al-Halabi H, Albrecht S, Jabado N, Eberhart CG, Grajkowska W, Weiss WA, Clifford SC, Bouffet E, Rutka JT, Korshunov A, Pfister S, Taylor MD. Northcott PA, et al. Among authors: clifford sc. Acta Neuropathol. 2011 Aug;122(2):231-40. doi: 10.1007/s00401-011-0846-7. Epub 2011 Jun 17. Acta Neuropathol. 2011. PMID: 21681522 Free PMC article.
Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance.
Jeyapalan JN, Noor DA, Lee SH, Tan CL, Appleby VA, Kilday JP, Palmer RD, Schwalbe EC, Clifford SC, Walker DA, Murray MJ, Coleman N, Nicholson JC, Scotting PJ. Jeyapalan JN, et al. Among authors: clifford sc. Br J Cancer. 2011 Aug 9;105(4):575-85. doi: 10.1038/bjc.2011.218. Epub 2011 Jun 28. Br J Cancer. 2011. PMID: 21712824 Free PMC article.
153 results