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Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways.
Deelen J, Uh HW, Monajemi R, van Heemst D, Thijssen PE, Böhringer S, van den Akker EB, de Craen AJ, Rivadeneira F, Uitterlinden AG, Westendorp RG, Goeman JJ, Slagboom PE, Houwing-Duistermaat JJ, Beekman M. Deelen J, et al. Age (Dordr). 2013 Feb;35(1):235-49. doi: 10.1007/s11357-011-9340-3. Epub 2011 Nov 24. Age (Dordr). 2013. PMID: 22113349 Free PMC article.
Association of the risk of osteoarthritis with high innate production of interleukin-1beta and low innate production of interleukin-10 ex vivo, upon lipopolysaccharide stimulation.
Riyazi N, Slagboom E, de Craen AJ, Meulenbelt I, Houwing-Duistermaat JJ, Kroon HM, van Schaardenburg D, Rosendaal FR, Breedveld FC, Huizinga TW, Kloppenburg M. Riyazi N, et al. Arthritis Rheum. 2005 May;52(5):1443-50. doi: 10.1002/art.21014. Arthritis Rheum. 2005. PMID: 15880595 Free article.
Urinary CTX-II levels are associated with radiographic subtypes of osteoarthritis in hip, knee, hand, and facet joints in subject with familial osteoarthritis at multiple sites: the GARP study.
Meulenbelt I, Kloppenburg M, Kroon HM, Houwing-Duistermaat JJ, Garnero P, Hellio Le Graverand MP, Degroot J, Slagboom PE. Meulenbelt I, et al. Ann Rheum Dis. 2006 Mar;65(3):360-5. doi: 10.1136/ard.2005.040642. Epub 2005 Aug 3. Ann Rheum Dis. 2006. PMID: 16079167 Free PMC article.
251 results