Gilmer JF - Search Results

1

Differential inhibition of tumour cell-induced platelet aggregation by the nicotinate aspirin prodrug (ST0702) and aspirin.

Medina C, Harmon S, Inkielewicz I, Santos-Martinez MJ, Jones M, Cantwell P, Bazou D, Ledwidge M, Radomski MW, Gilmer JF. Medina C, et al. Among authors: gilmer jf. Br J Pharmacol. 2012 Jun;166(3):938-49. doi: 10.1111/j.1476-5381.2011.01794.x. Br J Pharmacol. 2012. PMID: 22122360 Free PMC article.

2

Isosorbide-based aspirin prodrugs: integration of nitric oxide releasing groups.

Jones M, Inkielewicz I, Medina C, Santos-Martinez MJ, Radomski A, Radomski MW, Lally MN, Moriarty LM, Gaynor J, Carolan CG, Khan D, O'Byrne P, Harmon S, Holland V, Clancy JM, Gilmer JF. Jones M, et al. Among authors: gilmer jf. J Med Chem. 2009 Nov 12;52(21):6588-98. doi: 10.1021/jm900561s. J Med Chem. 2009. PMID: 19821574

3

Mechanisms of aggregation inhibition by aspirin and nitrate-aspirin prodrugs in human platelets.

Harmon S, Inkielewicz-Stepniak I, Jones M, Ledwidge M, Santos-Martinez MJ, Medina C, Radomski MW, Gilmer JF. Harmon S, et al. Among authors: gilmer jf. J Pharm Pharmacol. 2012 Jan;64(1):77-89. doi: 10.1111/j.2042-7158.2011.01380.x. Epub 2011 Nov 10. J Pharm Pharmacol. 2012. PMID: 22150675

4

In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin?

Ledwidge MT, Ryan F, Kerins DM, O'Connell D, Cefali G, Harmon S, Jones M, Gilmer JF. Ledwidge MT, et al. Among authors: gilmer jf. Atherosclerosis. 2012 Apr;221(2):478-83. doi: 10.1016/j.atherosclerosis.2012.01.016. Epub 2012 Jan 13. Atherosclerosis. 2012. PMID: 22326030

5

Discovery of a "true" aspirin prodrug.

Moriarty LM, Lally MN, Carolan CG, Jones M, Clancy JM, Gilmer JF. Moriarty LM, et al. Among authors: gilmer jf. J Med Chem. 2008 Dec 25;51(24):7991-9. doi: 10.1021/jm801094c. J Med Chem. 2008. PMID: 19049433

6

N-substituted homopiperazine barbiturates as gelatinase inhibitors.

Wang J, Medina C, Radomski MW, Gilmer JF. Wang J, et al. Among authors: gilmer jf. Bioorg Med Chem. 2011 Aug 15;19(16):4985-99. doi: 10.1016/j.bmc.2011.06.055. Epub 2011 Jun 25. Bioorg Med Chem. 2011. PMID: 21764590

7

Design of barbiturate-nitrate hybrids that inhibit MMP-9 activity and secretion.

Wang J, O'Sullivan S, Harmon S, Keaveny R, Radomski MW, Medina C, Gilmer JF. Wang J, et al. Among authors: gilmer jf. J Med Chem. 2012 Mar 8;55(5):2154-62. doi: 10.1021/jm201352k. Epub 2012 Feb 23. J Med Chem. 2012. PMID: 22248361

8

MMP inhibition by barbiturate homodimers.

Wang J, Radomski MW, Medina C, Gilmer JF. Wang J, et al. Among authors: gilmer jf. Bioorg Med Chem Lett. 2013 Jan 15;23(2):444-7. doi: 10.1016/j.bmcl.2012.11.063. Epub 2012 Nov 29. Bioorg Med Chem Lett. 2013. PMID: 23246356

9

Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK-MMP-9 pathway.

Radziwon-Balicka A, Santos-Martinez MJ, Corbalan JJ, O'Sullivan S, Treumann A, Gilmer JF, Radomski MW, Medina C. Radziwon-Balicka A, et al. Among authors: gilmer jf. Carcinogenesis. 2014 Feb;35(2):324-32. doi: 10.1093/carcin/bgt332. Epub 2013 Oct 1. Carcinogenesis. 2014. PMID: 24085798

10

Pharmacological characterization of nanoparticle-induced platelet microaggregation using quartz crystal microbalance with dissipation: comparison with light aggregometry.

Santos-Martinez MJ, Tomaszewski KA, Medina C, Bazou D, Gilmer JF, Radomski MW. Santos-Martinez MJ, et al. Among authors: gilmer jf. Int J Nanomedicine. 2015 Aug 13;10:5107-19. doi: 10.2147/IJN.S84305. eCollection 2015. Int J Nanomedicine. 2015. PMID: 26316743 Free PMC article.

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