Aladjem MI - Search Results

1

Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes.

Regairaz M, Zhang YW, Fu H, Agama KK, Tata N, Agrawal S, Aladjem MI, Pommier Y. Regairaz M, et al. Among authors: aladjem mi. J Cell Biol. 2011 Nov 28;195(5):739-49. doi: 10.1083/jcb.201104003. J Cell Biol. 2011. PMID: 22123861 Free PMC article.

2

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

Furuta T, Takemura H, Liao ZY, Aune GJ, Redon C, Sedelnikova OA, Pilch DR, Rogakou EP, Celeste A, Chen HT, Nussenzweig A, Aladjem MI, Bonner WM, Pommier Y. Furuta T, et al. Among authors: aladjem mi. J Biol Chem. 2003 May 30;278(22):20303-12. doi: 10.1074/jbc.M300198200. Epub 2003 Mar 25. J Biol Chem. 2003. PMID: 12660252 Free article.

3

Dynamic alterations of replication timing in mammalian cells.

Lin CM, Fu H, Martinovsky M, Bouhassira E, Aladjem MI. Lin CM, et al. Among authors: aladjem mi. Curr Biol. 2003 Jun 17;13(12):1019-28. doi: 10.1016/s0960-9822(03)00382-8. Curr Biol. 2003. PMID: 12814547 Free article.

4

Molecular interaction maps--a diagrammatic graphical language for bioregulatory networks.

Aladjem MI, Pasa S, Parodi S, Weinstein JN, Pommier Y, Kohn KW. Aladjem MI, et al. Sci STKE. 2004 Feb 24;2004(222):pe8. doi: 10.1126/stke.2222004pe8. Sci STKE. 2004. PMID: 14997004 Review.

5

The human beta-globin locus control region can silence as well as activate gene expression.

Feng YQ, Warin R, Li T, Olivier E, Besse A, Lobell A, Fu H, Lin CM, Aladjem MI, Bouhassira EE. Feng YQ, et al. Among authors: aladjem mi. Mol Cell Biol. 2005 May;25(10):3864-74. doi: 10.1128/MCB.25.10.3864-3874.2005. Mol Cell Biol. 2005. PMID: 15870261 Free PMC article.

6

Molecular interaction maps of bioregulatory networks: a general rubric for systems biology.

Kohn KW, Aladjem MI, Weinstein JN, Pommier Y. Kohn KW, et al. Among authors: aladjem mi. Mol Biol Cell. 2006 Jan;17(1):1-13. doi: 10.1091/mbc.e05-09-0824. Epub 2005 Nov 2. Mol Biol Cell. 2006. PMID: 16267266 Free PMC article.

7

p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

Furuta T, Hayward RL, Meng LH, Takemura H, Aune GJ, Bonner WM, Aladjem MI, Kohn KW, Pommier Y. Furuta T, et al. Among authors: aladjem mi. Oncogene. 2006 May 11;25(20):2839-49. doi: 10.1038/sj.onc.1209313. Oncogene. 2006. PMID: 16407843

8

Preventing gene silencing with human replicators.

Fu H, Wang L, Lin CM, Singhania S, Bouhassira EE, Aladjem MI. Fu H, et al. Among authors: aladjem mi. Nat Biotechnol. 2006 May;24(5):572-6. doi: 10.1038/nbt1202. Epub 2006 Apr 9. Nat Biotechnol. 2006. PMID: 16604060

9

Chk2 molecular interaction map and rationale for Chk2 inhibitors.

Pommier Y, Weinstein JN, Aladjem MI, Kohn KW. Pommier Y, et al. Among authors: aladjem mi. Clin Cancer Res. 2006 May 1;12(9):2657-61. doi: 10.1158/1078-0432.CCR-06-0743. Clin Cancer Res. 2006. PMID: 16675556

10

Depicting combinatorial complexity with the molecular interaction map notation.

Kohn KW, Aladjem MI, Kim S, Weinstein JN, Pommier Y. Kohn KW, et al. Among authors: aladjem mi. Mol Syst Biol. 2006;2:51. doi: 10.1038/msb4100088. Epub 2006 Oct 3. Mol Syst Biol. 2006. PMID: 17016517 Free PMC article. Review.

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