Chen L - Search Results

1

A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis.

Yoshizuka N, Chen RM, Xu Z, Liao R, Hong L, Hu WY, Yu G, Han J, Chen L, Sun P. Yoshizuka N, et al. Among authors: chen l, chen rm. Mol Cell Biol. 2012 Feb;32(3):606-18. doi: 10.1128/MCB.06301-11. Epub 2011 Nov 28. Mol Cell Biol. 2012. PMID: 22124154 Free PMC article.

2

The Mre11 complex mediates the S-phase checkpoint through an interaction with replication protein A.

Olson E, Nievera CJ, Liu E, Lee AY, Chen L, Wu X. Olson E, et al. Among authors: chen l. Mol Cell Biol. 2007 Sep;27(17):6053-67. doi: 10.1128/MCB.00532-07. Epub 2007 Jun 25. Mol Cell Biol. 2007. PMID: 17591703 Free PMC article.

3

Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.

Lee AY, Chiba T, Truong LN, Cheng AN, Do J, Cho MJ, Chen L, Wu X. Lee AY, et al. Among authors: chen l. J Biol Chem. 2012 Jan 20;287(4):2531-43. doi: 10.1074/jbc.M111.291104. Epub 2011 Nov 28. J Biol Chem. 2012. PMID: 22123827 Free PMC article.

4

The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.

Olson E, Nievera CJ, Lee AY, Chen L, Wu X. Olson E, et al. Among authors: chen l. J Biol Chem. 2007 Aug 3;282(31):22939-52. doi: 10.1074/jbc.M702162200. Epub 2007 May 25. J Biol Chem. 2007. PMID: 17526493 Free article.

5

The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair.

Wang H, Shi LZ, Wong CC, Han X, Hwang PY, Truong LN, Zhu Q, Shao Z, Chen DJ, Berns MW, Yates JR 3rd, Chen L, Wu X. Wang H, et al. Among authors: chen l, chen dj. PLoS Genet. 2013;9(2):e1003277. doi: 10.1371/journal.pgen.1003277. Epub 2013 Feb 28. PLoS Genet. 2013. PMID: 23468639 Free PMC article.

6

CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity.

Wang H, Li Y, Truong LN, Shi LZ, Hwang PY, He J, Do J, Cho MJ, Li H, Negrete A, Shiloach J, Berns MW, Shen B, Chen L, Wu X. Wang H, et al. Among authors: chen l. Mol Cell. 2014 Jun 19;54(6):1012-1021. doi: 10.1016/j.molcel.2014.04.012. Epub 2014 May 15. Mol Cell. 2014. PMID: 24837675 Free PMC article.

7

Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.

Chen L, Nievera CJ, Lee AY, Wu X. Chen L, et al. J Biol Chem. 2008 Mar 21;283(12):7713-20. doi: 10.1074/jbc.M710245200. Epub 2008 Jan 2. J Biol Chem. 2008. PMID: 18171670 Free article.

8

New cell therapy using bone marrow-derived stem cells/endothelial progenitor cells to accelerate neovascularization in healing of experimental ulcerative colitis.

Deng X, Szabo S, Chen L, Paunovic B, Khomenko T, Tolstanova G, Tarnawski AS, Jones MK, Sandor Z. Deng X, et al. Among authors: chen l. Curr Pharm Des. 2011;17(16):1643-51. doi: 10.2174/138161211796197007. Curr Pharm Des. 2011. PMID: 21548863 Review.

9

Inappropriate angiogenic response as a novel mechanism of duodenal ulceration and impaired healing.

Deng X, Xiong X, Khomenko T, Sandor Z, Osapay K, Tolstanova G, Shiloach J, Chen L, Folkman J, Szabo S. Deng X, et al. Among authors: chen l. Dig Dis Sci. 2011 Oct;56(10):2792-801. doi: 10.1007/s10620-011-1753-4. Epub 2011 Jul 7. Dig Dis Sci. 2011. PMID: 21735086 Free PMC article.

10

Neutralizing anti-vascular endothelial growth factor (VEGF) antibody reduces severity of experimental ulcerative colitis in rats: direct evidence for the pathogenic role of VEGF.

Tolstanova G, Khomenko T, Deng X, Chen L, Tarnawski A, Ahluwalia A, Szabo S, Sandor Z. Tolstanova G, et al. Among authors: chen l. J Pharmacol Exp Ther. 2009 Mar;328(3):749-57. doi: 10.1124/jpet.108.145128. Epub 2008 Dec 5. J Pharmacol Exp Ther. 2009. PMID: 19060224

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