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Development of ATP-competitive mTOR inhibitors.
Liu Q, Kang SA, Thoreen CC, Hur W, Wang J, Chang JW, Markhard A, Zhang J, Sim T, Sabatini DM, Gray NS. Liu Q, et al. Among authors: sabatini dm. Methods Mol Biol. 2012;821:447-60. doi: 10.1007/978-1-61779-430-8_29. Methods Mol Biol. 2012. PMID: 22125084 Free PMC article.
Huntingtin aggregates ask to be eaten.
Thoreen CC, Sabatini DM. Thoreen CC, et al. Among authors: sabatini dm. Nat Genet. 2004 Jun;36(6):553-4. doi: 10.1038/ng0604-553. Nat Genet. 2004. PMID: 15167929 No abstract available.
An expanding role for mTOR in cancer.
Guertin DA, Sabatini DM. Guertin DA, et al. Among authors: sabatini dm. Trends Mol Med. 2005 Aug;11(8):353-61. doi: 10.1016/j.molmed.2005.06.007. Trends Mol Med. 2005. PMID: 16002336 Review.
AMPK and p53 help cells through lean times.
Thoreen CC, Sabatini DM. Thoreen CC, et al. Among authors: sabatini dm. Cell Metab. 2005 May;1(5):287-8. doi: 10.1016/j.cmet.2005.04.009. Cell Metab. 2005. PMID: 16054073 Free article. Review.
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Sarbassov DD, Ali SM, Sengupta S, Sheen JH, Hsu PP, Bagley AF, Markhard AL, Sabatini DM. Sarbassov DD, et al. Among authors: sabatini dm. Mol Cell. 2006 Apr 21;22(2):159-68. doi: 10.1016/j.molcel.2006.03.029. Epub 2006 Apr 6. Mol Cell. 2006. PMID: 16603397 Free article.
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM. Sancak Y, et al. Among authors: sabatini dm. Mol Cell. 2007 Mar 23;25(6):903-15. doi: 10.1016/j.molcel.2007.03.003. Mol Cell. 2007. PMID: 17386266 Free article.
Defining the role of mTOR in cancer.
Guertin DA, Sabatini DM. Guertin DA, et al. Among authors: sabatini dm. Cancer Cell. 2007 Jul;12(1):9-22. doi: 10.1016/j.ccr.2007.05.008. Cancer Cell. 2007. PMID: 17613433 Free article. Review.
291 results