Meng L - Search Results

1

Discovery and bioactivity of 4-(2-arylpyrido[3',2':3,4]pyrrolo[1,2-f][1,2,4]triazin-4-yl) morpholine derivatives as novel PI3K inhibitors.

Wang J, Wang X, Chen Y, Chen S, Chen G, Tong L, Meng L, Xie Y, Ding J, Yang C. Wang J, et al. Among authors: meng l. Bioorg Med Chem Lett. 2012 Jan 1;22(1):339-42. doi: 10.1016/j.bmcl.2011.11.003. Epub 2011 Nov 9. Bioorg Med Chem Lett. 2012. PMID: 22130133

2

DNA damage, c-myc suppression and apoptosis induced by the novel topoisomerase II inhibitor, salvicine, in human breast cancer MCF-7 cells.

Lu HR, Meng LH, Huang M, Zhu H, Miao ZH, Ding J. Lu HR, et al. Cancer Chemother Pharmacol. 2005 Mar;55(3):286-94. doi: 10.1007/s00280-004-0877-z. Epub 2004 Nov 16. Cancer Chemother Pharmacol. 2005. PMID: 15592835

3

Emerging cancer therapeutic opportunities target DNA-repair systems.

Ding J, Miao ZH, Meng LH, Geng MY. Ding J, et al. Trends Pharmacol Sci. 2006 Jun;27(6):338-44. doi: 10.1016/j.tips.2006.04.007. Epub 2006 May 11. Trends Pharmacol Sci. 2006. PMID: 16697054 Review.

4

Salvicine, a novel topoisomerase II inhibitor, exerts its potent anticancer activity by ROS generation.

Meng LH, Ding J. Meng LH, et al. Acta Pharmacol Sin. 2007 Sep;28(9):1460-5. doi: 10.1111/j.1745-7254.2007.00698.x. Acta Pharmacol Sin. 2007. PMID: 17723179 Review.

5

Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.

Qin Y, Meng L, Hu C, Duan W, Zuo Z, Lin L, Zhang X, Ding J. Qin Y, et al. Among authors: meng l. Mol Cancer Ther. 2007 Sep;6(9):2429-40. doi: 10.1158/1535-7163.MCT-07-0147. Mol Cancer Ther. 2007. PMID: 17876042

6

ADAM15 suppresses cell motility by driving integrin alpha5beta1 cell surface expression via Erk inactivation.

Chen Q, Meng LH, Zhu CH, Lin LP, Lu H, Ding J. Chen Q, et al. Int J Biochem Cell Biol. 2008;40(10):2164-73. doi: 10.1016/j.biocel.2008.02.021. Epub 2008 Feb 26. Int J Biochem Cell Biol. 2008. PMID: 18387333

7

Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species.

Lu JJ, Meng LH, Cai YJ, Chen Q, Tong LJ, Lin LP, Ding J. Lu JJ, et al. Cancer Biol Ther. 2008 Jul;7(7):1017-23. doi: 10.4161/cbt.7.7.6035. Epub 2008 Apr 4. Cancer Biol Ther. 2008. PMID: 18414062 Free article.

8

The marine-derived oligosaccharide sulfate (MdOS), a novel multiple tyrosine kinase inhibitor, combats tumor angiogenesis both in vitro and in vivo.

Ma J, Xin X, Meng L, Tong L, Lin L, Geng M, Ding J. Ma J, et al. Among authors: meng l. PLoS One. 2008;3(11):e3774. doi: 10.1371/journal.pone.0003774. Epub 2008 Nov 20. PLoS One. 2008. PMID: 19020661 Free PMC article.

9

S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton.

Zhang C, Yang N, Yang CH, Ding HS, Luo C, Zhang Y, Wu MJ, Zhang XW, Shen X, Jiang HL, Meng LH, Ding J. Zhang C, et al. PLoS One. 2009;4(3):e4881. doi: 10.1371/journal.pone.0004881. Epub 2009 Mar 18. PLoS One. 2009. PMID: 19293927 Free PMC article.

10

Direct palladium-catalyzed arylations of aryl bromides with 2/9-substituted pyrimido[5,4-b]indolizines.

Jiang M, Li T, Meng L, Yang C, Xie Y, Ding J. Jiang M, et al. Among authors: meng l. J Comb Chem. 2009 Sep-Oct;11(5):806-8. doi: 10.1021/cc800162k. J Comb Chem. 2009. PMID: 19645499

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