Wang J - Search Results

1

Discovery and bioactivity of 4-(2-arylpyrido[3',2':3,4]pyrrolo[1,2-f][1,2,4]triazin-4-yl) morpholine derivatives as novel PI3K inhibitors.

Wang J, Wang X, Chen Y, Chen S, Chen G, Tong L, Meng L, Xie Y, Ding J, Yang C. Wang J, et al. Among authors: wang x. Bioorg Med Chem Lett. 2012 Jan 1;22(1):339-42. doi: 10.1016/j.bmcl.2011.11.003. Epub 2011 Nov 9. Bioorg Med Chem Lett. 2012. PMID: 22130133

2

WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant.

Li T, Wang J, Wang X, Yang N, Chen SM, Tong LJ, Yang CH, Meng LH, Ding J. Li T, et al. Among authors: wang x, wang j. J Pharmacol Exp Ther. 2010 Sep 1;334(3):830-8. doi: 10.1124/jpet.110.167940. Epub 2010 Jun 3. J Pharmacol Exp Ther. 2010. PMID: 20522531

3

Difuran-substituted quinoxalines as a novel class of PI3Kα H1047R mutant inhibitors: Synthesis, biological evaluation and structure-activity relationship.

Zhang N, Yu Z, Yang X, Zhou Y, Tang Q, Hu P, Wang J, Zhang SL, Wang MW, He Y. Zhang N, et al. Among authors: wang j, wang mw. Eur J Med Chem. 2018 Sep 5;157:37-49. doi: 10.1016/j.ejmech.2018.07.061. Epub 2018 Jul 29. Eur J Med Chem. 2018. PMID: 30071408

4

Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3Kα H1047R mutant inhibitors.

Zhang N, Yu Z, Yang X, Zhou Y, Wang J, Zhang SL, Wang MW, He Y. Zhang N, et al. Among authors: wang j, wang mw. Eur J Med Chem. 2018 Oct 5;158:707-719. doi: 10.1016/j.ejmech.2018.09.002. Epub 2018 Sep 6. Eur J Med Chem. 2018. PMID: 30245395

5

Synthesis, structure-activity relationships and preliminary antitumor evaluation of benzothiazole-2-thiol derivatives as novel apoptosis inducers.

Wang Z, Shi XH, Wang J, Zhou T, Xu YZ, Huang TT, Li YF, Zhao YL, Yang L, Yang SY, Yu LT, Wei YQ. Wang Z, et al. Among authors: wang j. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1097-101. doi: 10.1016/j.bmcl.2010.12.124. Epub 2010 Dec 31. Bioorg Med Chem Lett. 2011. PMID: 21262571

6

Synthesis and cytotoxic activity of novel 1-((indol-3-yl)methyl)-1H-imidazolium salts.

Xu XL, Wang J, Yu CL, Chen W, Li YC, Li Y, Zhang HB, Yang XD. Xu XL, et al. Among authors: wang j. Bioorg Med Chem Lett. 2014 Nov 1;24(21):4926-30. doi: 10.1016/j.bmcl.2014.09.045. Epub 2014 Sep 23. Bioorg Med Chem Lett. 2014. PMID: 25301771

7

Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors.

Wang Y, Huang W, Xin M, Chen P, Gui L, Zhao X, Tang F, Wang J, Liu F. Wang Y, et al. Among authors: wang j. Bioorg Med Chem. 2017 Jan 1;25(1):75-83. doi: 10.1016/j.bmc.2016.10.011. Epub 2016 Oct 11. Bioorg Med Chem. 2017. PMID: 27771180

8

Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of non-small cell lung cancer.

Wang X, Bai E, Zhou H, Sha S, Miao H, Qin Y, Liu Z, Wang J, Zhang H, Lei M, Liu J, Hai O, Zhu Y. Wang X, et al. Among authors: wang j. Bioorg Med Chem. 2019 Feb 1;27(3):533-544. doi: 10.1016/j.bmc.2018.12.036. Epub 2018 Dec 28. Bioorg Med Chem. 2019. PMID: 30606672

9

Effect of acidic oligosaccharide sugar chain on scopolamine-induced memory impairment in rats and its related mechanisms.

Fan Y, Hu J, Li J, Yang Z, Xin X, Wang J, Ding J, Geng M. Fan Y, et al. Among authors: wang j. Neurosci Lett. 2005 Feb 21;374(3):222-6. doi: 10.1016/j.neulet.2004.10.063. Epub 2004 Dec 10. Neurosci Lett. 2005. PMID: 15663967

10

Discovery of potent anti-inflammatory 4-(4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-yl) pyrimidin-2-amines for use as Janus kinase inhibitors.

Wang Y, Huang W, Xin M, Chen P, Gui L, Zhao X, Zhu X, Luo H, Cong X, Wang J, Liu F. Wang Y, et al. Among authors: wang j. Bioorg Med Chem. 2019 Jun 15;27(12):2592-2597. doi: 10.1016/j.bmc.2019.03.048. Epub 2019 Mar 25. Bioorg Med Chem. 2019. PMID: 30926315

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