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The C allele of rs5743836 polymorphism in the human TLR9 promoter links IL-6 and TLR9 up-regulation and confers increased B-cell proliferation.
Carvalho A, Osório NS, Saraiva M, Cunha C, Almeida AJ, Teixeira-Coelho M, Ludovico P, Pedrosa J, Pitzurra L, Aversa F, Romani L, Castro AG, Rodrigues F. Carvalho A, et al. Among authors: romani l. PLoS One. 2011;6(11):e28256. doi: 10.1371/journal.pone.0028256. Epub 2011 Nov 23. PLoS One. 2011. PMID: 22132241 Free PMC article.
The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma.
Carvalho A, Cunha C, Almeida AJ, Osório NS, Saraiva M, Teixeira-Coelho M, Pedreiro S, Torrado E, Domingues N, Gomes-Alves AG, Marques A, Lacerda JF, da Silva MG, Gomes M, Pinto AC, Torres F, Rendeiro P, Tavares P, Di Ianni M, Medeiros R, Heutink P, Bracci PM, Conde L, Ludovico P, Pedrosa J, Maciel P, Pitzurra L, Aversa F, Marques H, Paiva A, Skibola CF, Romani L, Castro AG, Rodrigues F. Carvalho A, et al. Among authors: romani l. Genes Immun. 2012 Feb;13(2):197-201. doi: 10.1038/gene.2011.59. Epub 2011 Aug 25. Genes Immun. 2012. PMID: 21866115 Free PMC article.
TLR9 activation dampens the early inflammatory response to Paracoccidioides brasiliensis, impacting host survival.
Menino JF, Saraiva M, Gomes-Alves AG, Lobo-Silva D, Sturme M, Gomes-Rezende J, Saraiva AL, Goldman GH, Cunha C, Carvalho A, Romani L, Pedrosa J, Castro AG, Rodrigues F. Menino JF, et al. Among authors: romani l. PLoS Negl Trop Dis. 2013 Jul 25;7(7):e2317. doi: 10.1371/journal.pntd.0002317. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23936560 Free PMC article.
Neutrophil responses to aspergillosis: new roles for old players.
Cunha C, Kurzai O, Löffler J, Aversa F, Romani L, Carvalho A. Cunha C, et al. Among authors: romani l. Mycopathologia. 2014 Dec;178(5-6):387-93. doi: 10.1007/s11046-014-9796-7. Epub 2014 Aug 9. Mycopathologia. 2014. PMID: 25106756 Review.
TLR3 essentially promotes protective class I-restricted memory CD8⁺ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients.
Carvalho A, De Luca A, Bozza S, Cunha C, D'Angelo C, Moretti S, Perruccio K, Iannitti RG, Fallarino F, Pierini A, Latgé JP, Velardi A, Aversa F, Romani L. Carvalho A, et al. Among authors: romani l. Blood. 2012 Jan 26;119(4):967-77. doi: 10.1182/blood-2011-06-362582. Epub 2011 Dec 6. Blood. 2012. PMID: 22147891 Free article.
569 results