Scott JE - Search Results

1

Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis.

Cronan MR, Nakamura K, Johnson NL, Granger DA, Cuevas BD, Wang JG, Mackman N, Scott JE, Dohlman HG, Johnson GL. Cronan MR, et al. Among authors: scott je. Oncogene. 2012 Aug 23;31(34):3889-900. doi: 10.1038/onc.2011.544. Epub 2011 Dec 5. Oncogene. 2012. PMID: 22139075 Free PMC article.

2

Homogeneous time-resolved fluorescence resonance energy transfer assay for measurement of Phox/Bem1p (PB1) domain heterodimerization.

Nakamura K, Zawistowski JS, Hughes MA, Sexton JZ, Yeh LA, Johnson GL, Scott JE. Nakamura K, et al. Among authors: scott je. J Biomol Screen. 2008 Jun;13(5):396-405. doi: 10.1177/1087057108318281. Epub 2008 May 14. J Biomol Screen. 2008. PMID: 18480472

3

Development and validation of a high-throughput intrinsic ATPase activity assay for the discovery of MEKK2 inhibitors.

Ahmad S, Hughes MA, Johnson GL, Scott JE. Ahmad S, et al. Among authors: scott je. J Biomol Screen. 2013 Apr;18(4):388-99. doi: 10.1177/1087057112466430. Epub 2012 Nov 7. J Biomol Screen. 2013. PMID: 23134735 Free PMC article.

4

Bosutinib reduces the efficacy of Dasatinib in triple-negative breast cancer cell lines.

Tarpley M, Abdissa TT, Johnson GL, Scott JE. Tarpley M, et al. Among authors: scott je. Anticancer Res. 2014 Apr;34(4):1629-35. Anticancer Res. 2014. PMID: 24692691 Free PMC article.

5

Identification of ponatinib and other known kinase inhibitors with potent MEKK2 inhibitory activity.

Ahmad S, Johnson GL, Scott JE. Ahmad S, et al. Among authors: scott je. Biochem Biophys Res Commun. 2015 Aug 7;463(4):888-93. doi: 10.1016/j.bbrc.2015.06.029. Epub 2015 Jun 6. Biochem Biophys Res Commun. 2015. PMID: 26056008 Free PMC article.

6

Discovery and characterization of an iminocoumarin scaffold as an inhibitor of MEKK2 (MAP3K2).

Ahmad S, St Hilaire VR, Dandepally SR, Johnson GL, Williams AL, Scott JE. Ahmad S, et al. Among authors: scott je. Biochem Biophys Res Commun. 2018 Jan 29;496(1):205-211. doi: 10.1016/j.bbrc.2018.01.027. Epub 2018 Jan 5. Biochem Biophys Res Commun. 2018. PMID: 29309787 Free PMC article.

7

CoAsy knockdown in TNBC cell lines resulted in no overt effect on cell proliferation in vitro.

Kharabsheh HA, Scott JE. Kharabsheh HA, et al. Among authors: scott je. Biochem Biophys Res Commun. 2020 Sep 10;530(1):136-141. doi: 10.1016/j.bbrc.2020.06.016. Epub 2020 Jul 31. Biochem Biophys Res Commun. 2020. PMID: 32828275 Free PMC article.

8

Identification of a Triple Drug Combination That Is Synergistically Cytotoxic for Triple-Negative Breast Cancer Cells Using a Novel Combination Discovery Approach.

Ahmad S, He Q, Williams KP, Scott JE. Ahmad S, et al. Among authors: scott je. SLAS Discov. 2020 Sep;25(8):923-938. doi: 10.1177/2472555220924478. Epub 2020 May 22. SLAS Discov. 2020. PMID: 32441190 Free PMC article.

9

Alleviating cancer drug toxicity by inhibiting a bacterial enzyme.

Wallace BD, Wang H, Lane KT, Scott JE, Orans J, Koo JS, Venkatesh M, Jobin C, Yeh LA, Mani S, Redinbo MR. Wallace BD, et al. Among authors: scott je. Science. 2010 Nov 5;330(6005):831-5. doi: 10.1126/science.1191175. Science. 2010. PMID: 21051639 Free PMC article.

10

MEKK2 mediates aberrant ERK activation in neurofibromatosis type I.

Bok S, Shin DY, Yallowitz AR, Eiseman M, Cung M, Xu R, Li N, Sun J, Williams AL, Scott JE, Su B, Shim JH, Greenblatt MB. Bok S, et al. Among authors: scott je. Nat Commun. 2020 Nov 11;11(1):5704. doi: 10.1038/s41467-020-19555-6. Nat Commun. 2020. PMID: 33177525 Free PMC article.

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