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Inflammatory lung injury is associated with endothelial cell mitochondrial fission and requires the nitration of RhoA and cytoskeletal remodeling.
Pokharel MD, Fu P, Garcia-Flores A, Yegambaram M, Lu Q, Sun X, Unwalla H, Aggarwal S, Fineman JR, Wang T, Black SM. Pokharel MD, et al. Among authors: black sm. Free Radic Biol Med. 2024 Aug 20;221:125-135. doi: 10.1016/j.freeradbiomed.2024.05.019. Epub 2024 May 10. Free Radic Biol Med. 2024. PMID: 38734269 Free article.
Inhalable Advanced Co-Spray Dried Microparticles/Nanoparticles of a Novel RhoA/Rho Kinase Inhibitor with Lung Surfactant Biomimetic Phospholipids for Targeted Lung Delivery.
Ruiz VH, Encinas-Basurto D, Ortega-Alarcon N, Eedara BB, Fineman JR, Black SM, Mansour HM. Ruiz VH, et al. Among authors: black sm. ACS Pharmacol Transl Sci. 2024 Oct 3;7(10):3241-3254. doi: 10.1021/acsptsci.4c00432. eCollection 2024 Oct 11. ACS Pharmacol Transl Sci. 2024. PMID: 39416970
The mitochondrial redistribution of ENOS is regulated by AKT1 and dimer status.
Sun X, Moreno Caceres S, Yegambaram M, Lu Q, Pokharel MD, Boehme JT, Datar SA, Aggarwal S, Wang T, Fineman JR, Black SM. Sun X, et al. Among authors: black sm. Nitric Oxide. 2024 Nov 1;152:90-100. doi: 10.1016/j.niox.2024.09.009. Epub 2024 Sep 25. Nitric Oxide. 2024. PMID: 39332480
414 results